EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.21 | additional information | activated by phosphorylation | Drosophila melanogaster | |
2.7.11.21 | additional information | activated by phosphorylation | Homo sapiens | |
2.7.11.21 | additional information | activated by phosphorylation | Saccharomyces cerevisiae | |
2.7.11.21 | additional information | activated by phosphorylation | Xenopus laevis | |
2.7.11.21 | additional information | activated by phosphorylation | Saccharomyces pombe |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.21 | ATP + a protein | Drosophila melanogaster | - |
ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | Homo sapiens | - |
ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | Saccharomyces cerevisiae | - |
ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | Xenopus laevis | - |
ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | Saccharomyces pombe | - |
ADP + a phosphoprotein | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.21 | Drosophila melanogaster | - |
- |
- |
2.7.11.21 | Homo sapiens | - |
- |
- |
2.7.11.21 | Saccharomyces cerevisiae | - |
- |
- |
2.7.11.21 | Saccharomyces pombe | - |
- |
- |
2.7.11.21 | Xenopus laevis | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.7.11.21 | phosphoprotein | - |
Drosophila melanogaster |
2.7.11.21 | phosphoprotein | - |
Homo sapiens |
2.7.11.21 | phosphoprotein | - |
Saccharomyces cerevisiae |
2.7.11.21 | phosphoprotein | - |
Xenopus laevis |
2.7.11.21 | phosphoprotein | - |
Saccharomyces pombe |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.21 | ATP + a protein | - |
Drosophila melanogaster | ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | - |
Homo sapiens | ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | - |
Saccharomyces cerevisiae | ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | - |
Xenopus laevis | ADP + a phosphoprotein | - |
? | |
2.7.11.21 | ATP + a protein | - |
Saccharomyces pombe | ADP + a phosphoprotein | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.21 | Cdc5 | - |
Saccharomyces cerevisiae |
2.7.11.21 | PLK | - |
Drosophila melanogaster |
2.7.11.21 | PLK | - |
Homo sapiens |
2.7.11.21 | Plo1 | - |
Saccharomyces pombe |
2.7.11.21 | Plx1 | - |
Xenopus laevis |
2.7.11.21 | polo-like kinase | - |
Drosophila melanogaster |
2.7.11.21 | polo-like kinase | - |
Homo sapiens |
2.7.11.21 | polo-like kinase | - |
Saccharomyces cerevisiae |
2.7.11.21 | polo-like kinase | - |
Xenopus laevis |
2.7.11.21 | polo-like kinase | - |
Saccharomyces pombe |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.21 | ATP | - |
Drosophila melanogaster | |
2.7.11.21 | ATP | - |
Homo sapiens | |
2.7.11.21 | ATP | - |
Saccharomyces cerevisiae | |
2.7.11.21 | ATP | - |
Xenopus laevis | |
2.7.11.21 | ATP | - |
Saccharomyces pombe |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.7.11.21 | Homo sapiens | up-regulated in many tumors | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.11.21 | physiological function | Plks are potent regulators of M phase, their roles in mitotic entry, spindle pole functions and cytokinesis are broadly conserved | Drosophila melanogaster |
2.7.11.21 | physiological function | Plks are potent regulators of M phase, their roles in mitotic entry, spindle pole functions and cytokinesis are broadly conserved | Homo sapiens |
2.7.11.21 | physiological function | Plks are potent regulators of M phase, their roles in mitotic entry, spindle pole functions and cytokinesis are broadly conserved | Saccharomyces cerevisiae |
2.7.11.21 | physiological function | Plks are potent regulators of M phase, their roles in mitotic entry, spindle pole functions and cytokinesis are broadly conserved | Xenopus laevis |
2.7.11.21 | physiological function | Plks are potent regulators of M phase, their roles in mitotic entry, spindle pole functions and cytokinesis are broadly conserved | Saccharomyces pombe |