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Literature summary extracted from

  • Dawson, A.; Fyfe, P.K.; Hunter, W.N.
    Specificity and reactivity in menaquinone biosynthesis: the structure of Escherichia coli MenD (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase) (2008), J. Mol. Biol., 384, 1353-1368.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.2.1.9 sitting and hanging vapor diffusion method, hexagonal complex with thiamine diphosphate and Mn2+ Escherichia coli K-12

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.2.1.9 61400
-
 gel filtration Escherichia coli K-12

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.9 Escherichia coli K-12 P17109
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.2.1.9 Ni2+ affinity column, size-exclusion column Escherichia coli K-12

Subunits

EC Number Subunits Comment Organism
2.2.1.9 ? dimer or tetramer Escherichia coli K-12

Synonyms

EC Number Synonyms Comment Organism
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase
-
 Escherichia coli K-12
2.2.1.9 EcMenD
-
 Escherichia coli K-12
2.2.1.9 MenD
-
 Escherichia coli K-12

Cofactor

EC Number Cofactor Comment Organism Structure
2.2.1.9 thiamine diphosphate
-
 Escherichia coli K-12

General Information

EC Number General Information Comment Organism
2.2.1.9 physiological function first enzyme in biosynthesis of menaquinone or vitamin K2, influence on electron transport in bacteria Escherichia coli K-12