Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Polakof, S.; Miguez, J.M.; Soengas, J.L.
    A hepatic protein modulates glucokinase activity in fish and avian liver: a comparative study (2009), J. Comp. Physiol. B, 179, 643-652.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.1 glucokinase regulatory protein inhibits competitively GCK activity with D-glucose, inhibition of glucokinase activity by glucokinase regulatory protein in vivo is enhanced by fructose 6-phosphate or sorbitol 6-phosphate Carassius auratus
2.7.1.1 glucokinase regulatory protein inhibits competitively GCK activity with D-glucose, inhibition of glucokinase activity by glucokinase regulatory protein in vivo is enhanced by fructose 6-phosphate or sorbitol 6-phosphate Cyprinus carpio
2.7.1.1 glucokinase regulatory protein inhibits competitively GCK activity with D-glucose, inhibition of glucokinase activity by glucokinase regulatory protein in vivo is enhanced by fructose 6-phosphate or sorbitol 6-phosphate Gallus gallus
2.7.1.1 glucokinase regulatory protein inhibits competitively GCK activity with D-glucose, inhibition of glucokinase activity by glucokinase regulatory protein in vivo is enhanced by fructose 6-phosphate or sorbitol 6-phosphate Oncorhynchus mykiss
2.7.1.1 glucokinase regulatory protein inhibits competitively GCK activity with D-glucose, inhibition of glucokinase activity by glucokinase regulatory protein in vivo is enhanced by fructose 6-phosphate or sorbitol 6-phosphate Rattus norvegicus
2.7.1.1 additional information not inhibited by D-glucose 6-phosphate Carassius auratus
2.7.1.1 additional information not inhibited by D-glucose 6-phosphate Cyprinus carpio
2.7.1.1 additional information not inhibited by D-glucose 6-phosphate Gallus gallus
2.7.1.1 additional information not inhibited by D-glucose 6-phosphate Oncorhynchus mykiss
2.7.1.1 additional information not inhibited by D-glucose 6-phosphate Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.1 K+ increases the activity of glucokinase Gallus gallus
2.7.1.1 K+ increases the activity of glucokinase Rattus norvegicus
2.7.1.1 K+ increases the activity of glucokinase Carassius auratus
2.7.1.1 K+ increases the activity of glucokinase Cyprinus carpio
2.7.1.1 K+ increases the activity of glucokinase Oncorhynchus mykiss

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.1 Carassius auratus
-
-
-
2.7.1.1 Cyprinus carpio
-
-
-
2.7.1.1 Gallus gallus
-
-
-
2.7.1.1 Oncorhynchus mykiss
-
-
-
2.7.1.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.1 liver
-
 Gallus gallus
-
2.7.1.1 liver
-
 Rattus norvegicus
-
2.7.1.1 liver
-
 Carassius auratus
-
2.7.1.1 liver
-
 Cyprinus carpio
-
2.7.1.1 liver
-
 Oncorhynchus mykiss
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.1 ATP + D-glucose
-
 Gallus gallus ADP + D-glucose 6-phosphate
-
 ?
2.7.1.1 ATP + D-glucose
-
 Rattus norvegicus ADP + D-glucose 6-phosphate
-
 ?
2.7.1.1 ATP + D-glucose
-
 Carassius auratus ADP + D-glucose 6-phosphate
-
 ?
2.7.1.1 ATP + D-glucose
-
 Cyprinus carpio ADP + D-glucose 6-phosphate
-
 ?
2.7.1.1 ATP + D-glucose
-
 Oncorhynchus mykiss ADP + D-glucose 6-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.1 GCK
-
 Gallus gallus
2.7.1.1 GCK
-
 Rattus norvegicus
2.7.1.1 GCK
-
 Carassius auratus
2.7.1.1 GCK
-
 Cyprinus carpio
2.7.1.1 GCK
-
 Oncorhynchus mykiss
2.7.1.1 glucokinase
-
 Gallus gallus
2.7.1.1 glucokinase
-
 Rattus norvegicus
2.7.1.1 glucokinase
-
 Carassius auratus
2.7.1.1 glucokinase
-
 Cyprinus carpio
2.7.1.1 glucokinase
-
 Oncorhynchus mykiss

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.1 ATP
-
 Gallus gallus
2.7.1.1 ATP
-
 Rattus norvegicus
2.7.1.1 ATP
-
 Carassius auratus
2.7.1.1 ATP
-
 Cyprinus carpio
2.7.1.1 ATP
-
 Oncorhynchus mykiss