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Literature summary extracted from

  • Yamamoto, E.; Watanabe, Y.; Makino, Y.; Omichi, K.
    Ispection of the activator binding site for 4-alpha-glucanotransferase in porcine liver glycogen debranching enzyme with fluorogenic dextrins (2009), J. Biochem., 145, 585-590.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.25 alpha-cyclodextrin activates GDE in liver Sus scrofa
2.4.1.25 beta-cyclodextrin activates GDE in liver Sus scrofa
2.4.1.25 gamma-cyclodextrin activates GDE in liver Sus scrofa
3.2.1.33 Glcalpha1-6Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4GlcPA
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.25 Sus scrofa
-
-
-
3.2.1.33 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.25 liver
-
 Sus scrofa
-
3.2.1.33 liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.25 Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha(1,4)(Glc-alpha-(1,4)-Glc-alpha-(1,4)Glc-alpha-(1,4)-Glc-alpha-(1,6))Glc-alpha-(1,4)-Glc-alpha(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-(1-deoxy-1-[(2-pyridyl)amino]-D-glucitol) i.e. B5/84 + G6PA Sus scrofa Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)(Glc-alpha-(1,6))Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-(1-deoxy-1-[(2-pyridyl)amino]-D-glucitol) + Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-Glc-alpha-(1,4)-(1-deoxy-1-[(2-pyridyl)amino]-D-glucitol)
-
 ?
3.2.1.33 Glcalpha1-4Glcalpha1-4Glcalpha1-4(Glcalpha1-6)Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4-(1-deoxy-1-[(2-pyridyl)amino]-D-glucitol) + H2O
-
 Sus scrofa Glcapha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4-(1-deoxy-1-[(2-pyridyl)amino]-D-glucitol) + D-glucose
-
 ?
3.2.1.33 Glcalpha1-6Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4Glcalpha1-4GlcPA + H2O
-
 Sus scrofa ?
-
 ?
3.2.1.33 additional information fluorogenic dextrins with non-reducing-end isomaltosyl residues, Glcalpha1-6Glcalpha1-4(Glcalpha1-4)nGlcPA, are not hydrolysed by the GDE amylo-alpha-1,6-glucosidase found in porcine liver Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.25 GDE
-
 Sus scrofa
2.4.1.25 glycogen debranching enzyme
-
 Sus scrofa
2.4.1.25 More GDE is a member of the alpha-amylase family Sus scrofa
3.2.1.33 amylo-alpha-1,6-glucosidase activity
-
 Sus scrofa
3.2.1.33 dextrin 6-alpha-glucosidase
-
 Sus scrofa
3.2.1.33 GDE
-
 Sus scrofa
3.2.1.33 glycogen debranching enzyme
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.25 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.25 6
-
 assay at Sus scrofa