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Literature summary extracted from

  • Subramanian, T.; Liu, S.; Troutman, J.M.; Andres, D.A.; Spielmann, H.P.
    Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity (2008), ChemBioChem, 9, 2872-2882.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.58 0.0001
-
 (2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.00017
-
 (2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.00026
-
 (2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0003
-
 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.00034
-
 (2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0004
-
 (2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0004
-
 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate apparent Michaelis-Menten constant for peptide, determined by continuous fluorescence assay Rattus norvegicus
2.5.1.58 0.00042
-
 (2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0005
-
 (2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0005
-
 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate apparent Michaelis-Menten constant for peptide, determined by RP-HPLC product analysis Rattus norvegicus
2.5.1.58 0.0007
-
 (2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0008
-
 (2E,6E)-farnesyl diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0009
-
 (2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0009
-
 (2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0009
-
 (2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.001
-
 (2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.001
-
 (2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.001
-
 (2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0011
-
 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0013
-
 (2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0013
-
 (2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0013
-
 (2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0013
-
 (2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0013
-
 (2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0014
-
 (2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0017
-
 (2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0019
-
 (2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.002
-
 (2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.002
-
 (2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0021
-
 (2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0021
-
 (2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0023
-
 (2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0023
-
 (2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0023
-
 (2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0025
-
 (2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0031
-
 (2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0031
-
 (2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0032
-
 (2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0038
-
 (2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0038
-
 (2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.004
-
 (2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.004
-
 (2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.004
-
 (2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0043
-
 (2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0044
-
 (2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0045
-
 (2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0063
-
 (2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.007
-
 (2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.008
-
 (2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.01
-
 (2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate value above, apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0102
-
 (2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.015
-
 (2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0165
-
 (2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0187
-
 (2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0214
-
 (2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.027
-
 geranyl diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.03
-
 (2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.033
-
 (2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.0512
-
 (2E,6E)-3,7-dimethyl-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus
2.5.1.58 0.07
-
 (2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent Michaelis-Menten constant for peptide Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.58 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.58 (2E,6E)-3,7-dimethyl-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(3,4,5-trimethoxybenzyl)oxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(3,4,5-trimethoxybenzyl)oxy]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-y)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yll)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yll)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yll)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate
-
 ?
2.5.1.58 (2E,6E)-farnesyl diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLS + diphosphate
-
 ?
2.5.1.58 geranyl diphosphate + dansyl-GCVLS
-
 Rattus norvegicus dansyl-G-(S-geranyl)CVLS + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.58 FTase
-
 Rattus norvegicus
2.5.1.58 protein farnesyl transferase
-
 Rattus norvegicus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.5.1.58 0.004
-
 geranyl diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.004
-
 (2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.01
-
 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate apparent turnover number, measured by continuous fluorescence assay Rattus norvegicus
2.5.1.58 0.03
-
 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.04
-
 (2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.04
-
 (2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.06
-
 (2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.069
-
 (2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.07
-
 (2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.08
-
 (2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.088
-
 (2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.095
-
 (2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.1
-
 (2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.1
-
 (2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.11
-
 (2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.11
-
 (2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.11
-
 (2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.12
-
 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate apparent turnover number, determined by RP-HPLC product analysis Rattus norvegicus
2.5.1.58 0.13
-
 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.13
-
 (2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.13
-
 (2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.14
-
 (2E,6E)-farnesyl diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.15
-
 (2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.16
-
 (2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.166
-
 (2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.17
-
 (2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.17
-
 (2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.17
-
 (2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.17
-
 (2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.17
-
 (2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.19
-
 (2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.19
-
 (2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.21
-
 (2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.23
-
 (2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.24
-
 (2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.24
-
 (2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.27
-
 (2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.27
-
 (2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.27
-
 (2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.28
-
 (2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.3
-
 (2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.3
-
 (2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.3
-
 (2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.3
-
 (2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.4
-
 (2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.4
-
 (2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.44
-
 (2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.44
-
 (2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.5
-
 (2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.53
-
 (2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.55
-
 (2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.58
-
 (2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.6
-
 (2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 0.7
-
 (2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 1.15
-
 (2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 1.4
-
 (2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 1.6
-
 (2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 1.67
-
 (2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 1.93
-
 (2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus
2.5.1.58 3.1
-
 (2E,6E)-3,7-dimethyl-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate apparent turnover number Rattus norvegicus

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.5.1.58 9
-
 (2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 15
-
 geranyl diphosphate
-
 Rattus norvegicus
2.5.1.58 20
-
 (2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 21
-
 (2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 24
-
 (2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 28
-
 (2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 30
-
 (2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 40
-
 (2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 42
-
 (2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 50
-
 (2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 50
-
 (2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 60
-
 (2E,6E)-3,7-dimethyl-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 60
-
 (2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 60
-
 (2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 68
-
 (2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 80
-
 (2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 80
-
 (2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 80
-
 (2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 80
-
 (2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 85
-
 (2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 87
-
 (2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 93
-
 (2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 100
-
 (2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 100
-
 (2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 100
-
 (2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 100
-
 (2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 107
-
 (2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 110
-
 (2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 110
-
 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 110
-
 (2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 115
-
 (2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 120
-
 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 120
-
 (2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 120
-
 (2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 120
-
 (2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 120
-
 (2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 120
-
 (2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 130
-
 (2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 130
-
 (2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 130
-
 (2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 140
-
 (2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 150
-
 (2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 150
-
 (2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 150
-
 (2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate determined by continuous fluorescence assay Rattus norvegicus
2.5.1.58 160
-
 (2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 160
-
 (2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 160
-
 (2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate
-
 Rattus norvegicus
2.5.1.58 160
-
 (2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 160
-
 (2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate determined by RP-HPLC product analysis Rattus norvegicus
2.5.1.58 170
-
 (2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 170
-
 (2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 180
-
 (2E,6E)-farnesyl diphosphate
-
 Rattus norvegicus
2.5.1.58 180
-
 (2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 190
-
 (2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 190
-
 (2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 200
-
 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate measured by continuous fluorescence assay Rattus norvegicus
2.5.1.58 240
-
 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate determined by RP-HPLC product analysis Rattus norvegicus
2.5.1.58 260
-
 (2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate
-
 Rattus norvegicus
2.5.1.58 260
-
 (2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 350
-
 (2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus
2.5.1.58 380
-
 (2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate
-
 Rattus norvegicus