EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.12 | 6-O-dodecylsulfonyl-D-glucose 2,4-bisphosphate | - |
Rattus norvegicus | |
3.1.4.12 | 6-O-ethylsulfonyl-D-glucose 2,4-bisphosphate | - |
Rattus norvegicus | |
3.1.4.12 | 6-O-hexylsulfonyl-D-glucose 2,4-bisphosphate | - |
Rattus norvegicus | |
3.1.4.12 | 6-O-octylsulfonyl-D-glucose 2,4-bisphosphate | - |
Rattus norvegicus | |
3.1.4.12 | phosphatidylinositol 3,5-bisphosphate | potent inhibitor | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.12 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.4.12 | Mono Q column chromatography | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.4.12 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.12 | sphingomyelin + H2O | - |
Rattus norvegicus | N-acylsphingosine + choline phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.4.12 | acid sphingomyelinase | - |
Rattus norvegicus |
3.1.4.12 | aSMase | - |
Rattus norvegicus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.1.4.12 | 0.00044 | - |
in 100 mM NaOAc, pH 5.2, at 37°C | Rattus norvegicus | 6-O-dodecylsulfonyl-D-glucose 2,4-bisphosphate | |
3.1.4.12 | 0.00234 | - |
in 100 mM NaOAc, pH 5.2, at 37°C | Rattus norvegicus | 6-O-octylsulfonyl-D-glucose 2,4-bisphosphate | |
3.1.4.12 | 0.00416 | - |
in 100 mM NaOAc, pH 5.2, at 37°C | Rattus norvegicus | 6-O-hexylsulfonyl-D-glucose 2,4-bisphosphate | |
3.1.4.12 | 0.0396 | - |
in 100 mM NaOAc, pH 5.2, at 37°C | Rattus norvegicus | 6-O-ethylsulfonyl-D-glucose 2,4-bisphosphate |