Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lee, J.Y.; Jeong, K.W.; Lee, J.U.; Kang, D.I.; Kim, Y.
    Novel E. coli beta-ketoacyl-acyl carrier protein synthase III inhibitors as targeted antibiotics (2009), Bioorg. Med. Chem., 17, 1506-1513.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.180 gene fabH, expression in Escherichia coli strain BL21(DE3) Escherichia coli K-12

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.180 3-[(1E)-N-(4-methyl-1,3-thiazol-2-yl)ethanehydrazonoyl]phenol i.e. YKA3003 Escherichia coli K-12
2.3.1.180 3-[2-(3,4-dihydroxyphenyl)-1-methyl-2-oxoethyl]-6,7-dimethoxy-2-benzofuran-1(3H)-one i.e. YKA3001 Escherichia coli K-12
2.3.1.180 4-[(E)-(cyclohexylimino)methyl]benzene-1,3-diol i.e. YKA3013 Escherichia coli K-12
2.3.1.180 additional information inhibitor design, structures, and binding analysis, antibacterial activities, overview Escherichia coli K-12

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.180 Escherichia coli K-12
-
 gene fabH
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.180 beta-ketoacyl-acyl carrier protein synthase III
-
 Escherichia coli K-12
2.3.1.180 KAS III
-
 Escherichia coli K-12

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.180 8
-
 assay at Escherichia coli K-12

General Information

EC Number General Information Comment Organism
2.3.1.180 physiological function KAS III is a condensing enzyme that initiates fatty acid biosynthesis Escherichia coli K-12