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Literature summary extracted from

  • Lipskaya, T.Y.; Voinova, V.V.
    Reversibility of nucleoside diphosphate kinase solubilization from the surface of the outer mitochondrial membrane (2009), Biochemistry, 74, 578-587.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.7.4.6 NDPK becomes sensitive to proteolysis only after its solubilization, NDPK solubilization from the outer membrane of liver mitochondria could be partially reversed by the addition of 3.3 mM MgCl2, complete rebinding of the enzyme after the addition of MgCl2 is observed when the mitochondrial washing and storage medium contains leupeptin Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.4.6 mitochondrial membrane
-
 Rattus norvegicus 31966
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.6 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.6 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.6 ATP + ADP
-
 Rattus norvegicus ADP + ATP
-
 ?
2.7.4.6 ATP + CDP
-
 Rattus norvegicus ADP + CTP
-
 ?
2.7.4.6 ATP + UDP
-
 Rattus norvegicus ADP + UTP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.4.6 NDPK
-
 Rattus norvegicus
2.7.4.6 nucleoside diphosphate kinase
-
 Rattus norvegicus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.7.4.6 6 8 the rate of the enzyme solubilization is dependent on the pH of the storage medium (pH 6.0-8.0), it decreases with increase in pH Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.4.6 ATP
-
 Rattus norvegicus