EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.13.9 | - |
Pseudomonas fluorescens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.13.9 | benzoylalanine | KMO inhibitor that mimics the substrate structure, and also stimulates reduction of the flavin by NADPH | Pseudomonas fluorescens | |
1.14.13.9 | m-nitrobenzoylalanine | KMO inhibitor that mimics the substrate structure, and also stimulates reduction of the flavin by NADPH | Pseudomonas fluorescens | |
1.14.13.9 | additional information | targeted inhibition of KMO is a viable strategy for achieving local elevation of kynurenate concentrations | Pseudomonas fluorescens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.13.9 | NaCl | stabilizes | Pseudomonas fluorescens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.13.9 | Pseudomonas fluorescens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.13.9 | - |
Pseudomonas fluorescens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.13.9 | L-kynurenine + NADPH + O2 | binding of L-kynurenine to the oxidized enzyme is relatively slow and involves at least two reversible steps | Pseudomonas fluorescens | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.13.9 | KMO | - |
Pseudomonas fluorescens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.13.9 | FAD | - |
Pseudomonas fluorescens | |
1.14.13.9 | NADPH | - |
Pseudomonas fluorescens |