Literature summary extracted from

Molchanov, S.; Gryff-Keller, A.
Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione (2009), Acta Biochim. Pol., 56, 447-454.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.13.11.27	2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione	is a selective and efficient herbicide that can be applied as a medicine in a hereditary metabolic disease - tyrosinemia type I	Pseudomonas fluorescens

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.13.11.27	Fe2+	-	Pseudomonas fluorescens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.11.27	4-hydroxyphenylpyruvate + O2	Pseudomonas fluorescens	-	homogentisate + CO2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.27	Pseudomonas fluorescens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.27	4-hydroxyphenylpyruvate + O2	-	Pseudomonas fluorescens	homogentisate + CO2	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.13.11.27	homotrimer	-	Pseudomonas fluorescens

Synonyms

EC Number	Synonyms	Comment	Organism
1.13.11.27	4-hydroxyphenylpyruvate dioxygenase	-	Pseudomonas fluorescens
1.13.11.27	HPPD	-	Pseudomonas fluorescens

General Information

EC Number	General Information	Comment	Organism
1.13.11.27	metabolism	inhibition mechanism of 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione	Pseudomonas fluorescens

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Release 2023.1 (January 2023)