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Literature summary extracted from

  • Li, J.; Bewley, J.D.; Hua, Z.; Zheng, W.; Wang, A.
    Model and molecular dynamic simulations of active and inactive endo-beta-1,4-mannanase in tomato fruit (2008), Protein J., 27, 363-370.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.2.1.78 molecular dynamic simulation of wild-type and mutant lacking the C-terminal amino acid residues 394-399, SerLysLeuSer. The inactive form has a lower stability than the active one. The loss of amino acids from the C-terminal end of the protein indirectly affects the conformation of the catalytic Glu318 residue and stability of active site because of interactions between residues at the C-terminus and the rest of protein Solanum lycopersicum

Protein Variants

EC Number Protein Variants Comment Organism
3.2.1.78 additional information the cultivar Walter displays an inactive enzyme due to the absence of the C-terminal four amino acid residues 394-399, SerLysLeuSer. The inactive form has a lower stability than the active one. The loss of amino acids from the C-terminal end of the protein indirectly affects the conformation of the catalytic Glu318 residue and stability of active site because of interactions between residues at the C-terminus and the rest of protein Solanum lycopersicum

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.78 Solanum lycopersicum Q8L5J1
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.78 fruit
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Solanum lycopersicum
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