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Literature summary extracted from

  • Ziegler, J.; Facchini, P.J.; Geissler, R.; Schmidt, J.; Ammer, C.; Kramell, R.; Voigtlaender, S.; Gesell, A.; Pienkny, S.; Brandt, W.
    Evolution of morphine biosynthesis in opium poppy (2009), Phytochemistry, 70, 1696-1707.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.248 heterologously overexpressed in its active form from Papaver somniferum Papaver somniferum

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.248 Papaver arenarium
-
-
-
1.1.1.248 Papaver bracteatum A4UHT7
-
-
1.1.1.248 Papaver pilosum
-
-
-
1.1.1.248 Papaver pyrenaicum
-
-
-
1.1.1.248 Papaver somniferum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.248 additional information occurrence of active SalR homologue in Papaver pilosum, although it does not produce salutaridine or any other promorphinan alkaloid Papaver pilosum ?
-
 ?
1.1.1.248 additional information occurrence of active SalR homologue in Papaver pyrenaicum, although it does not produce salutaridine or any other promorphinan alkaloid Papaver pyrenaicum ?
-
 ?
1.1.1.248 salutaridine + NADPH + H+ high levels of SalR expression in all Papaver somniferum varieties Papaver somniferum (7S)-salutaridinol + NADP+
-
 ?
1.1.1.248 salutaridine + NADPH + H+ moderate levels of SalR expression in Papaver arenarium Papaver arenarium (7S)-salutaridinol + NADP+
-
 ?
1.1.1.248 salutaridine + NADPH + H+ moderate levels of SalR expression in Papaver bracteatum Papaver bracteatum (7S)-salutaridinol + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.248 SalR
-
 Papaver somniferum
1.1.1.248 SalR
-
 Papaver bracteatum
1.1.1.248 SalR
-
 Papaver arenarium
1.1.1.248 SalR
-
 Papaver pilosum
1.1.1.248 SalR
-
 Papaver pyrenaicum

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.248 NADPH
-
 Papaver somniferum
1.1.1.248 NADPH
-
 Papaver bracteatum
1.1.1.248 NADPH
-
 Papaver arenarium
1.1.1.248 NADPH
-
 Papaver pilosum
1.1.1.248 NADPH
-
 Papaver pyrenaicum