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Literature summary extracted from

  • Kolaczkowski, M.; Kolaczkowska, A.; Sroda, K.; Ramalhete, C.; Michalak, K.; Mulhovo, S.; Ferreira, M.J.
    Substrates and modulators of the multidrug transporter Cdr1p of Candida albicans in antifungal extracts of medicinal plants (2010), Mycoses, 53, 305-310.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.6.2.2 gene cdr1, overexpression in Saccharaomyces cerevisiae Candida albicans
7.6.2.2 gene cdr1, overexpression in Saccharaomyces cerevisiae Nakaseomyces glabratus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.6.2.2 ATP + H2O + xenobiotic/in Candida albicans
-
 ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in Nakaseomyces glabratus
-
 ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in Candida albicans CCM8320
-
 ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in Nakaseomyces glabratus CCM8270
-
 ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 additional information Candida albicans the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
 ?
7.6.2.2 additional information Nakaseomyces glabratus the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
 ?
7.6.2.2 additional information Candida albicans CCM8320 the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
 ?
7.6.2.2 additional information Nakaseomyces glabratus CCM8270 the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.2 Candida albicans
-
-
-
7.6.2.2 Candida albicans CCM8320
-
-
-
7.6.2.2 Nakaseomyces glabratus
-
-
-
7.6.2.2 Nakaseomyces glabratus CCM8270
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.2 ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds Candida albicans ADP + phosphate + ketoconazole/out
-
 ?
7.6.2.2 ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds Nakaseomyces glabratus ADP + phosphate + ketoconazole/out
-
 ?
7.6.2.2 ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds Candida albicans CCM8320 ADP + phosphate + ketoconazole/out
-
 ?
7.6.2.2 ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds Nakaseomyces glabratus CCM8270 ADP + phosphate + ketoconazole/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in
-
 Candida albicans ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in
-
 Nakaseomyces glabratus ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in
-
 Candida albicans CCM8320 ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 ATP + H2O + xenobiotic/in
-
 Nakaseomyces glabratus CCM8270 ADP + phosphate + xenobiotic/out
-
 ?
7.6.2.2 additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview Candida albicans ?
-
 ?
7.6.2.2 additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview Nakaseomyces glabratus ?
-
 ?
7.6.2.2 additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview Candida albicans CCM8320 ?
-
 ?
7.6.2.2 additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview Nakaseomyces glabratus CCM8270 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.6.2.2 Cdr1p
-
 Candida albicans
7.6.2.2 Cdr1p
-
 Nakaseomyces glabratus
7.6.2.2 additional information Cdr1p is a multidrug transporter of the ATP-binding cassette superfamily Candida albicans
7.6.2.2 additional information Cdr1p is a multidrug transporter of the ATP-binding cassette superfamily Nakaseomyces glabratus
7.6.2.2 multidrug transporter
-
 Candida albicans
7.6.2.2 multidrug transporter
-
 Nakaseomyces glabratus