EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.4.24.29 | T85R/L86Y | mutation at the site of autocatalytic activation in the propeptide. Mutation results in secretion of an intact N-terminal propeptide with degradation of the M4 metalloprotease domain. The segment of the fungalysin-thermolysin-propeptide domain promotes intracellular processing of proaureolysin while bestowing a chaperone function | Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.29 | Staphylococcus aureus | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.4.24.29 | proteolytic modification | mutation T85R/L86Y at the site of autocatalytic activation in the propeptide results in secretion of an intact N-terminal propeptide with degradation of the M4 metalloprotease domain. The fungalysin-thermolysin-propeptide domain promotes intracellular processing of proaureolysin while bestowing a chaperone function | Staphylococcus aureus |