EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.19.4 | into pBluescript II SK+ and subsequently into pFLAG-Act1 | Candida albicans |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.19.18 | (4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ | Candida albicans | - |
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O | - |
? | |
1.14.19.18 | (4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ | Candida albicans TUA6 | - |
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O | - |
? | |
1.14.19.29 | (E)-sphing-4-enine + ferrocytochrome b5 + O2 + H+ | Candida albicans | - |
(4E,8E)-sphinga-4,8-dienine + ferricytochrome b5 + H2O | - |
? | |
1.14.19.29 | (E)-sphing-4-enine + ferrocytochrome b5 + O2 + H+ | Candida albicans TUA6 | - |
(4E,8E)-sphinga-4,8-dienine + ferricytochrome b5 + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.19.4 | Candida albicans | - |
- |
- |
1.14.19.18 | Candida albicans | - |
- |
- |
1.14.19.29 | Candida albicans | - |
- |
- |
1.14.19.29 | Candida albicans TUA6 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.19.4 | (E)-sphing-4-enine + reduced acceptor + O2 | - |
Candida albicans | (2S,3R,4E,8E)-2-aminooctadeca-4,8-diene-1,3-diol + acceptor + H2O | - |
? | |
1.14.19.4 | (E)-sphing-4-enine + reduced acceptor + O2 | - |
Candida albicans TUA6 | (2S,3R,4E,8E)-2-aminooctadeca-4,8-diene-1,3-diol + acceptor + H2O | - |
? | |
1.14.19.18 | (4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans | (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O | - |
? | |
1.14.19.18 | (4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans TUA6 | (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O | - |
? | |
1.14.19.29 | (E)-sphing-4-enine + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans | (4E,8E)-sphinga-4,8-dienine + ferricytochrome b5 + H2O | - |
? | |
1.14.19.29 | (E)-sphing-4-enine + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans TUA6 | (4E,8E)-sphinga-4,8-dienine + ferricytochrome b5 + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.19.4 | Ca-SLDp | - |
Candida albicans |
1.14.19.4 | SLD | - |
Candida albicans |
1.14.19.4 | sphingolipid DELTA8-desaturase | - |
Candida albicans |
1.14.19.18 | DELTA8-sphingolipid desaturase | - |
Candida albicans |
1.14.19.18 | SLD | - |
Candida albicans |
1.14.19.29 | SLD | - |
Candida albicans |
1.14.19.29 | sphingolipid DELTA8-desaturase | - |
Candida albicans |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.19.18 | cytochrome b5 | - |
Candida albicans |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.19.18 | physiological function | disruption of the DELTA8-sphingolipid desaturase gene leads to a decreased hyphal growth rate compared with the wild type strain | Candida albicans |
1.14.19.29 | malfunction | gene disruption leads to a decreased hyphal growth rate and increased sensitivity against SDS compared with the wild type strain | Candida albicans |