Literature summary extracted from

Olszanecki, R.; Bujak-Gizycka, B.; Madej, J.; Suski, M.; Wolkow, P.P.; Jawien, J.; Korbut, R.
Kaempferol, but not resveratrol inhibits angiotensin converting enzyme (2008), J. Physiol. Pharmacol., 59, 387-392.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.15.1	kaempferol	dose-dependent inhibition, 46% inhibition at 0.1 mM	Rattus norvegicus
3.4.15.1	additional information	not inhibited by resveratrol	Rattus norvegicus
3.4.15.1	perindoprilat	strong inhibitor	Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.15.1	angiotensin I + H2O	Rattus norvegicus	-	angiotensin II + L-His-L-Leu	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.15.1	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.15.1	aorta	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.15.1	angiotensin I + H2O	-	Rattus norvegicus	angiotensin II + L-His-L-Leu	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.15.1	ACE	-	Rattus norvegicus
3.4.15.1	angiotensin converting enzyme	-	Rattus norvegicus

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Release 2023.1 (January 2023)