EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | diclofenac sodium | competitive inhibition | Homo sapiens | |
1.8.1.7 | etomidate | competitive inhibition | Homo sapiens | |
1.8.1.7 | Ketoprofen | competitive inhibition | Homo sapiens | |
1.8.1.7 | lornoxicam | competitive inhibition | Homo sapiens | |
1.8.1.7 | morphine | competitive inhibition | Homo sapiens | |
1.8.1.7 | propofol | noncompetitive inhibition | Homo sapiens | |
1.8.1.7 | tenoxicam | competitive inhibition | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.7 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.1.7 | ammonium sulfate precipitation, 2',5'-ADP Sepharose 4B column chromatography and Sephadex G-200 gel filtration | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.8.1.7 | erythrocyte | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.8.1.7 | 0.0097 | - |
hemolysate, at 25°C, pH 8.0 | Homo sapiens |
1.8.1.7 | 20.75 | - |
after 2139fold purification, at 25°C, pH 8.0 | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.7 | glutathione disulfide + NADPH + H+ | - |
Homo sapiens | glutathione + NADP+ | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.7 | glutathione reductase | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | FAD | - |
Homo sapiens | |
1.8.1.7 | NADPH | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.8.1.7 | 0.0165 | - |
morphine | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | |
1.8.1.7 | 0.0725 | - |
etomidate | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | |
1.8.1.7 | 0.13 | - |
tenoxicam | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | |
1.8.1.7 | 0.418 | - |
propofol | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | |
1.8.1.7 | 0.42 | - |
lornoxicam | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | |
1.8.1.7 | 22.14 | - |
Ketoprofen | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | |
1.8.1.7 | 23.97 | - |
diclofenac sodium | in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.8.1.7 | 0.0128 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | morphine | |
1.8.1.7 | 0.0523 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | etomidate | |
1.8.1.7 | 0.082 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | tenoxicam | |
1.8.1.7 | 0.242 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | propofol | |
1.8.1.7 | 0.3 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | lornoxicam | |
1.8.1.7 | 6.278 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | Ketoprofen | |
1.8.1.7 | 7.265 | - |
in 100 mM Tris-HCl buffer, pH 8.0, at 25°C | Homo sapiens | diclofenac sodium |