EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | amikacin | - |
Homo sapiens | |
1.8.1.7 | amoxicillin | - |
Homo sapiens | |
1.8.1.7 | clindamycin | - |
Homo sapiens | |
1.8.1.7 | Lincomycin | - |
Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | ceftazidime | competitive inhibition | Homo sapiens | |
1.8.1.7 | ceftriaxone | competitive inhibition | Homo sapiens | |
1.8.1.7 | cefuroxime | competitive inhibition | Homo sapiens | |
1.8.1.7 | chloramphenicol | competitive inhibition | Homo sapiens | |
1.8.1.7 | Imipenem | competitive inhibition | Homo sapiens | |
1.8.1.7 | ornidazole | competitive inhibition | Homo sapiens | |
1.8.1.7 | rifamycin | competitive inhibition | Homo sapiens | |
1.8.1.7 | sulfanylacetamide | competitive inhibition | Homo sapiens | |
1.8.1.7 | Vancomycin | noncompetitive inhibition | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.7 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.1.7 | ammonium sulfate precipitation, 2',5'-ADP Sepharose 4B column chromatography and Sephadex G-200 gel filtration | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.8.1.7 | erythrocyte | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.8.1.7 | 0.01 | - |
hemolysate, at 25°C, pH 8.0 | Homo sapiens |
1.8.1.7 | 28 | - |
after 2800fold purification, at 25°C, pH 8.0 | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.7 | glutathione disulfide + NADPH + H+ | - |
Homo sapiens | glutathione + NADP+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.7 | EC 1.6.4.2 | formerly | Homo sapiens |
1.8.1.7 | glutathione reductase | - |
Homo sapiens |
1.8.1.7 | NADPH:oxidized glutathione oxidoreductase | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | FAD | - |
Homo sapiens | |
1.8.1.7 | NADPH | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.8.1.7 | 0.06 | - |
Imipenem | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 0.085 | - |
sulfanylacetamide | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 0.275 | - |
rifamycin | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 3.59 | - |
ceftazidime | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 3.71 | - |
ceftriaxone | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 3.85 | - |
chloramphenicol | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 15.11 | - |
Vancomycin | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 23.5 | - |
cefuroxime | at 25°C, pH 8.0 | Homo sapiens | |
1.8.1.7 | 28.49 | - |
ornidazole | at 25°C, pH 8.0 | Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.8.1.7 | 0.03 | - |
at 25°C, pH 8.0 | Homo sapiens | Imipenem | |
1.8.1.7 | 0.146 | - |
at 25°C, pH 8.0 | Homo sapiens | rifamycin | |
1.8.1.7 | 0.59 | - |
at 25°C, pH 8.0 | Homo sapiens | sulfanylacetamide | |
1.8.1.7 | 2.36 | - |
at 25°C, pH 8.0 | Homo sapiens | chloramphenicol | |
1.8.1.7 | 2.476 | - |
at 25°C, pH 8.0 | Homo sapiens | ceftazidime | |
1.8.1.7 | 2.88 | - |
at 25°C, pH 8.0 | Homo sapiens | ceftriaxone | |
1.8.1.7 | 4.83 | - |
at 25°C, pH 8.0 | Homo sapiens | Vancomycin | |
1.8.1.7 | 15.43 | - |
at 25°C, pH 8.0 | Homo sapiens | cefuroxime | |
1.8.1.7 | 19.63 | - |
at 25°C, pH 8.0 | Homo sapiens | ornidazole |