EC Number | Cloned (Comment) | Organism |
---|---|---|
1.8.98.2 | the vectors pcDNA3 and pFLAG-CMV2 are used, a leader sequence is cloned into the N-terminus coding region of Srx | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.8.98.2 | C99S | catalytic cysteine mutant | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.8.98.2 | cytosol | cytosolic Srx is translocated into the mitochondria under oxidative conditions | Homo sapiens | 5829 | - |
1.8.98.2 | mitochondrion | - |
Homo sapiens | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + R-SH | Homo sapiens | - |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.98.2 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.8.98.2 | A-549 cell | - |
Homo sapiens | - |
1.8.98.2 | HEK-293 cell | - |
Homo sapiens | - |
1.8.98.2 | HeLa cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + R-SH | - |
Homo sapiens | peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.98.2 | Srx | - |
Homo sapiens |
1.8.98.2 | sulfiredoxin | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.98.2 | ATP | - |
Homo sapiens |