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Literature summary extracted from

  • Willing, B.P.; Van Kessel, A.G.
    Intestinal microbiota differentially affect brush border enzyme activity and gene expression in the neonatal gnotobiotic pig (2008), J. Anim. Physiol. Anim. Nutr. (Berl.), 93, 586-595.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.62 additional information LPH expression appears to fall off in the villus tip of germfree pigs. LPH activity to gene expression ratio is lower in pigs conventionalized with faecal bacteria or monoassociatied with Escherichia coli compared with germfree pigs. LPH activity to gene expression ratio in pigs monoassociatied with Lactobacillus fermentum is similar to germfree pigs whereas in pigs monoassociatied with Lactobacillus fermentum and contaminated with Klebsiella pneumoniae the ratio is similar to pigs monoassociatied with Escherichia coli Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.62 Sus scrofa
-
-
-
3.2.1.108 Sus scrofa Q29587
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.62 enterocyte LPH activity to gene expression ratio is lower in pigs conventionalized with faecal bacteria or monoassociatied with Escherichia coli compared with germfree pigs. LPH activity to gene expression ratio in pigs monoassociatied with Lactobacillus fermentum is similar to germfree pigs whereas in pigs monoassociatied with Lactobacillus fermentum and contaminated with Klebsiella pneumoniae the ratio is similar to pigs monoassociatied with Escherichia coli Sus scrofa
-
3.2.1.108 enterocyte
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.108 additional information
-
 analysis of lactase phlorizin hydrolase activity in germfree, Lactobacillus fermentum or Escherichia coli monoassociated, Klebsiella pneumoniae LF diassociated and conventional pigs (measuring the amount of D-glucose liberated from lactose). Lowest lactase phlorizin hydrolase activity is observed in pigs, monoassociated with Lactobacillus fermentum. Lactase phlorizin hydrolase activity to mRNA ratio is reduced in enterocytes of pigs monoassociated with Lactobacillus fermentum as compared with germfree pigs Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.108 lactose + H2O
-
 Sus scrofa D-glucose + D-galactose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.62 lactase phlorizin hydrolase
-
 Sus scrofa
3.2.1.62 LPH
-
 Sus scrofa
3.2.1.108 lactase phlorizin hydrolase
-
 Sus scrofa
3.2.1.108 LPH
-
 Sus scrofa