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Literature summary extracted from
- Rho GTPase controls invagination and cohesive migration of the Drosophila salivary gland through Crumbs and Rho-kinase (2008), Dev. Biol., 321, 88-100.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.5.2 | additional information | Drosophila melanogaster | Rho1 activity is required for proper development of the circular visceral mesoderm upon which the gland migrates, Rho1 GTPase regulates salivary gland invagination by maintaining apical localization of Crumbs, Drosophila atypical protein kinase C and Stardust and that this occurs partially through regulation of Crumbs RNA level and apical localization of the transcript and by inducing apical constriction and cell shape change through Rho-kinase | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.5.2 | Drosophila melanogaster | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.6.5.2 | embryo | - |
Drosophila melanogaster | - |
| 3.6.5.2 | salivary gland | - |
Drosophila melanogaster | - |
| 3.6.5.2 | salivary gland epithelium | embryonic | Drosophila melanogaster | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.5.2 | additional information | Rho1 activity is required for proper development of the circular visceral mesoderm upon which the gland migrates, Rho1 GTPase regulates salivary gland invagination by maintaining apical localization of Crumbs, Drosophila atypical protein kinase C and Stardust and that this occurs partially through regulation of Crumbs RNA level and apical localization of the transcript and by inducing apical constriction and cell shape change through Rho-kinase | Drosophila melanogaster | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.6.5.2 | Rho GTPase | - |
Drosophila melanogaster |
| 3.6.5.2 | Rho1 | - |
Drosophila melanogaster |
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Release 2023.1 (January 2023)
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