Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Daiber, A.; Wenzel, P.; Oelze, M.; Schuhmacher, S.; Jansen, T.; Muenzel, T.
    Mitochondrial aldehyde dehydrogenase (ALDH-2)--maker of and marker for nitrate tolerance in response to nitroglycerin treatment (2009), Chem. Biol. Interact., 178, 40-47.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.2.1.3 medicine white blood cell ALDH activity is a reliable marker for organic nitrate tachyphylaxis and may be a useful marker for clinical tolerance as well Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.3 benomyl
-
Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.3 mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.3 an aldehyde + NAD+ + H2O Homo sapiens
-
an acid + NADH + H+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 artery
-
Homo sapiens
-
1.2.1.3 lymphocyte
-
Homo sapiens
-
1.2.1.3 monocyte
-
Homo sapiens
-
1.2.1.3 neutrophil
-
Homo sapiens
-
1.2.1.3 vein
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 2-hydroxy-3-nitrobenzaldehyde + NAD+ + H2O
-
Homo sapiens 2-hydroxy-3-nitrobenzoic acid + NADH + H+
-
?
1.2.1.3 an aldehyde + NAD+ + H2O
-
Homo sapiens an acid + NADH + H+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.3 aldehyde dehydrogenase
-
Homo sapiens
1.2.1.3 ALDH-2
-
Homo sapiens
1.2.1.3 mitochondrial aldehyde dehydrogenase
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 NAD+
-
Homo sapiens