Literature summary extracted from

Macauley, S.R.; Zimmerman, S.A.; Apolinario, E.E.; Evilia, C.; Hou, Y.M.; Ferry, J.G.; Sowers, K.R.
The archetype gamma-class carbonic anhydrase (Cam) contains iron when synthesized in vivo (2009), Biochemistry, 48, 817-819.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.2.1.1	expressed in Escherichia coli and Methanosarcina acetivorans	Methanosarcina thermophila

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
4.2.1.1	Fe2+	contains one iron ion per monomer when synthesized in Methanosarcina acetivorans	Methanosarcina thermophila
4.2.1.1	Zn2+	contains one zinc ion per monomer when overproduced in Escherichia coli	Methanosarcina thermophila

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.1	Methanosarcina thermophila	-	-	-

Oxidation Stability

EC Number	Oxidation Stability	Organism
4.2.1.1	the enzyme produced in vivo is sensitive to oxygen, losing 90% of activity in 5 min after exposure to air	Methanosarcina thermophila

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.1	CO2 + H2O	-	Methanosarcina thermophila	H2CO3	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
4.2.1.1	Cam	-	Methanosarcina thermophila
4.2.1.1	carbonic anhydrase	-	Methanosarcina thermophila

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Release 2023.1 (January 2023)