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Literature summary extracted from

  • Bonner, M.K.; Skop, A.R.
    Cell division screens and dynamin (2008), Biochem. Soc. Trans., 36, 431-435.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.5.5 Golgi apparatus isoform Dyn2aa is localized to plasma membrane and Golgi apparatus Drosophila melanogaster 5794
-
3.6.5.5 Golgi apparatus isoform Dyn2aa is localized to plasma membrane and Golgi apparatus Caenorhabditis elegans 5794
-
3.6.5.5 plasma membrane
-
Saccharomyces cerevisiae 5886
-
3.6.5.5 plasma membrane
-
Danio rerio 5886
-
3.6.5.5 plasma membrane isoform Dyn2ab is restricetd to the plasma membrane while isoform Dyn2aa is localized to plasma membrane and Golgi apparatus Drosophila melanogaster 5886
-
3.6.5.5 plasma membrane isoform Dyn2ab is restricetd to the plasma membrane while isoform Dyn2aa is localized to plasma membrane and Golgi apparatus Caenorhabditis elegans 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.5.5 additional information Drosophila melanogaster dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. ?
-
?
3.6.5.5 additional information Caenorhabditis elegans dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. ?
-
?
3.6.5.5 additional information Danio rerio dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.6.5.5 Caenorhabditis elegans
-
-
-
3.6.5.5 Caenorhabditis elegans P39055
-
-
3.6.5.5 Danio rerio
-
-
-
3.6.5.5 Drosophila melanogaster
-
-
-
3.6.5.5 Saccharomyces cerevisiae
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.5.5 epithelial cell
-
Drosophila melanogaster
-
3.6.5.5 epithelial cell
-
Caenorhabditis elegans
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.5.5 GTP + H2O
-
Drosophila melanogaster GDP + phosphate
-
?
3.6.5.5 GTP + H2O
-
Saccharomyces cerevisiae GDP + phosphate
-
?
3.6.5.5 GTP + H2O
-
Caenorhabditis elegans GDP + phosphate
-
?
3.6.5.5 GTP + H2O
-
Danio rerio GDP + phosphate
-
?
3.6.5.5 additional information dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. Drosophila melanogaster ?
-
?
3.6.5.5 additional information dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. Caenorhabditis elegans ?
-
?
3.6.5.5 additional information dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. Danio rerio ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.6.5.5 Dyn1 isoform Drosophila melanogaster
3.6.5.5 Dyn1 isoform Danio rerio
3.6.5.5 Dyn1 isoform Caenorhabditis elegans
3.6.5.5 DYN2 isoform Drosophila melanogaster
3.6.5.5 DYN2 isoform Caenorhabditis elegans
3.6.5.5 DYN2 isoform Danio rerio
3.6.5.5 Dyn2aa isoform Drosophila melanogaster
3.6.5.5 Dyn2aa isoform Caenorhabditis elegans
3.6.5.5 Dyn2aa isoform Danio rerio
3.6.5.5 Dyn2ab isoform Drosophila melanogaster
3.6.5.5 Dyn2ab isoform Caenorhabditis elegans
3.6.5.5 Dyn2ab isoform Danio rerio
3.6.5.5 Dyn3 isoform Drosophila melanogaster
3.6.5.5 Dyn3 isoform Caenorhabditis elegans
3.6.5.5 Dyn3 isoform Danio rerio
3.6.5.5 dynamin 1 isoform, originally identified as a microtubule-binding protein Drosophila melanogaster
3.6.5.5 dynamin 1 isoform, originally identified as a microtubule-binding protein Danio rerio
3.6.5.5 dynamin 1 isoform, originally identified as a microtubule-binding protein Caenorhabditis elegans
3.6.5.5 dynamin 2 isoform, plays a key role in endocytosis, actin dynamics, and membrane trafficking and is the only isoform that functions during cytokinesis Drosophila melanogaster
3.6.5.5 dynamin 2 isoform, plays a key role in endocytosis, actin dynamics, and membrane trafficking and is the only isoform that functions during cytokinesis Caenorhabditis elegans
3.6.5.5 dynamin 2 isoform, plays a key role in endocytosis, actin dynamics, and membrane trafficking and is the only isoform that functions during cytokinesis Danio rerio
3.6.5.5 dynamin 3 isoform Drosophila melanogaster
3.6.5.5 dynamin 3 isoform Caenorhabditis elegans
3.6.5.5 dynamin 3 isoform Danio rerio
3.6.5.5 Vps1p required for normal actin organization Saccharomyces cerevisiae