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Literature summary extracted from

  • Gruntenko, N.E.; Karpova, E.K.; Chentsova, N.A.; Adonyeva, N.V.; Rauschenbach, I.Y.
    20-hydroxyecdysone and juvenile hormone influence tyrosine hydroxylase activity in Drosophila females under normal and heat stress conditions (2009), Arch. Insect Biochem. Physiol., 72, 263-272.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.16.2 20-hydroxyecdysone 20-hydroxyecdysone feeding (0.06 mg) leads to a substantial rise in tyrosine hydroxylase activity Drosophila virilis
1.14.16.2 20-hydroxyecdysone 20-hydroxyecdysone feeding (0.06 mg) leads to a substantial rise in tyrosine hydroxylase activity Drosophila melanogaster
1.14.16.2 juvenile hormone-III 0.0001 or 0.0002 mg juvenile hormone-III application leads to a substantial rise in tyrosine hydroxylase activity Drosophila virilis
1.14.16.2 juvenile hormone-III 0.0001 or 0.0002 mg juvenile hormone-III application leads to a substantial rise in tyrosine hydroxylase activity Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
1.14.16.2 Drosophila melanogaster
-
-
-
1.14.16.2 Drosophila melanogaster Canton S
-
-
-
1.14.16.2 Drosophila virilis
-
-
-
1.14.16.2 Drosophila virilis 101
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.16.2 L-tyrosine + 5,6,7,8-tetrahydro-L-biopterin + O2
-
 Drosophila virilis 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydro-L-biopterin
-
 ?
1.14.16.2 L-tyrosine + 5,6,7,8-tetrahydro-L-biopterin + O2
-
 Drosophila melanogaster 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydro-L-biopterin
-
 ?
1.14.16.2 L-tyrosine + 5,6,7,8-tetrahydro-L-biopterin + O2
-
 Drosophila melanogaster Canton S 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydro-L-biopterin
-
 ?
1.14.16.2 L-tyrosine + 5,6,7,8-tetrahydro-L-biopterin + O2
-
 Drosophila virilis 101 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydro-L-biopterin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.16.2 tyrosine hydroxylase
-
 Drosophila virilis
1.14.16.2 tyrosine hydroxylase
-
 Drosophila melanogaster

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.16.2 5,6,7,8-tetrahydro-L-biopterin
-
 Drosophila virilis
1.14.16.2 5,6,7,8-tetrahydro-L-biopterin
-
 Drosophila melanogaster