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Literature summary extracted from
- Aconitase overexpression changes the product ratio of citric acid production by Yarrowia lipolytica (2009), Appl. Microbiol. Biotechnol., 81, 1087-1096.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 4.2.1.3 | gene ACO1, overexpression in strain H222, high-level expression of ACO in the ACO1 multicopy integrative transformant results in a shift of the citric acid/isocitric acid product pattern into the direction of isocitric acid | Yarrowia lipolytica |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.3 | cis-aconitate + H2O | Yarrowia lipolytica | - |
isocitrate | - |
? |  |
| 4.2.1.3 | citrate | Yarrowia lipolytica | - |
cis-aconitate + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.3 | Yarrowia lipolytica | - |
several strains, gene ACO1 | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.3 | additional information | the carbon source, e.g. glucose, sucrose, glycerol, or sunflower oil, influences the citrate/isocitrate ratio in the cells, overview | Yarrowia lipolytica | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.3 | cis-aconitate + H2O | - |
Yarrowia lipolytica | isocitrate | - |
? | |
| 4.2.1.3 | citrate | - |
Yarrowia lipolytica | cis-aconitate + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.1.3 | ACO | - |
Yarrowia lipolytica |
| 4.2.1.3 | aconitase | - |
Yarrowia lipolytica |
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Release 2023.1 (January 2023)
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