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Literature summary extracted from

  • Chiou, S.Y.; Lin, M.C.; Hwang, M.T.; Chang, H.G.; Lin, G.
    Benzene-di-N-substituted carbamates as conformationally constrained substrate analogs of cholesterol esterase (2008), Protein J., 27, 276-282.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.13 benzene-1,2-di-N-benzylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,2-di-N-n-butylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,2-di-N-n-hexylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,2-di-N-n-octylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,2-di-N-t-butylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,3-di-N-benzylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,3-di-N-n-butylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,3-di-N-n-hexylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,3-di-N-n-octylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,3-di-N-t-butylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,4-di-N-benzylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,4-di-N-n-butylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,4-di-N-n-hexylcarbamate pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,4-di-N-octylcarbamates pseudo substrate inhibitor Sus scrofa
3.1.1.13 benzene-1,4-di-N-t-butylcarbamate pseudo substrate inhibitor Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.13 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.13 pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.13 p-nitrophenyl butyrate + H2O
-
 Sus scrofa p-nitrophenol + butyrate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.13 CEase
-
 Sus scrofa
3.1.1.13 cholesterol esterase
-
 Sus scrofa

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.13 0.0004
-
 benzene-1,3-di-N-n-octylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.0007
-
 benzene-1,4-di-N-n-octylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.001
-
 benzene-1,3-di-N-n-hexylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.0012
-
 benzene-1,3-di-N-n-butylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.0012
-
 benzene-1,4-di-N-n-hexylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.0016
-
 benzene-1,3-di-N-t-butylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.0017
-
 benzene-1,3-di-N-benzylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.0018
-
 benzene-1,4-di-N-n-butylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.002
-
 benzene-1,4-di-N-t-butylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.004
-
 benzene-1,2-di-N-benzylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.005
-
 benzene-1,4-di-N-benzylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.007
-
 benzene-1,2-di-N-n-octylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.02
-
 benzene-1,2-di-N-n-hexylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.027
-
 benzene-1,2-di-N-n-butylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa
3.1.1.13 0.03
-
 benzene-1,2-di-N-t-butylcarbamate in sodium phosphate buffer (0.1 M, pH 7.0), at 25°C Sus scrofa