EC Number | Application | Comment | Organism |
---|---|---|---|
2.7.10.1 | medicine | tyrosine phosphorylation events mediated by aberrant activation of RTK pathways are proven to be involved in the development of several diseases including cancer. 70% of tyrosine phosphorylation events are conserved in human orthologs and paralogs | Homo sapiens |
2.7.10.1 | additional information | around 38% tyrosine phosphorylation events from Drosophila RTK proteins conserved on 185 human proteins are confirmed in vivo tyrosine phosphorylation events | Drosophila melanogaster |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.10.1 | Drosophila S2 cells stably transfected with human ErbB1 | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.10.1 | Drosophila melanogaster | P09208 | - |
- |
2.7.10.1 | Homo sapiens | P35916 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.10.1 | S2 cell | - |
Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.10.1 | additional information | ErbB1 receptor shows three phosphorylation sites (Y1110, Y1172 and Y1192) | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.10.1 | EGF receptor | - |
Homo sapiens |
2.7.10.1 | EGF RTK | - |
Homo sapiens |
2.7.10.1 | ERBB1 | - |
Homo sapiens |
2.7.10.1 | InR | - |
Drosophila melanogaster |
2.7.10.1 | insulin RTK | - |
Drosophila melanogaster |
2.7.10.1 | insulin-like receptor | - |
Drosophila melanogaster |
2.7.10.1 | receptor tyrosine kinase | - |
Drosophila melanogaster |
2.7.10.1 | receptor tyrosine kinase | - |
Homo sapiens |
2.7.10.1 | RTK | - |
Drosophila melanogaster |
2.7.10.1 | RTK | - |
Homo sapiens |