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Literature summary extracted from

  • Xiang, Y.; Takeo, S.; Florens, L.; Hughes, S.E.; Huo, L.J.; Gilliland, W.D.; Swanson, S.K.; Teeter, K.; Schwartz, J.W.; Washburn, M.P.; Jaspersen, S.L.; Hawley, R.S.
    The inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle (2007), PLoS Biol., 5, e323.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.21 the polo fragment is cloned into pBluescript and subcloned into the pUASP vector to generate transgenic flies Drosophila melanogaster

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.21 matrimony the matrimony protein acts as a negative regulator of polo during the later stages of G2 arrest during meiosis Drosophila melanogaster

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.21 centromere
-
 Drosophila melanogaster
-
-
2.7.11.21 chromosome
-
 Drosophila melanogaster 5694
-
2.7.11.21 nucleus
-
 Drosophila melanogaster 5634
-
2.7.11.21 spindle
-
 Drosophila melanogaster 5819
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.21 ATP + protein Drosophila melanogaster
-
 ADP + phosphoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.21 Drosophila melanogaster P52304
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.21 cystocyte
-
 Drosophila melanogaster
-
2.7.11.21 germarium
-
 Drosophila melanogaster
-
2.7.11.21 oocyte
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.21 ATP + Cdc25
-
 Drosophila melanogaster ADP + phosphorylated Cdc25
-
 ?
2.7.11.21 ATP + protein
-
 Drosophila melanogaster ADP + phosphoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.21 Polo kinase
-
 Drosophila melanogaster