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Literature summary extracted from
- Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product (2008), Org. Lett., 10, 2529-2532.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 5.4.99.7 | F699C | inactive | Saccharomyces cerevisiae |
| 5.4.99.7 | F699Q | inactive | Saccharomyces cerevisiae |
| 5.4.99.7 | F699S | inactive | Saccharomyces cerevisiae |
| 5.4.99.7 | F699T | the mutant produces protosta-13(17),24-dien-3beta-ol from (S)-2,3-oxidosqualene | Saccharomyces cerevisiae |
| 5.4.99.7 | F699Y | inactive | Saccharomyces cerevisiae |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.99.7 | Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.7 | (S)-2,3-oxidosqualene | - |
Saccharomyces cerevisiae | lanosterol | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.99.7 | ERG7 | - |
Saccharomyces cerevisiae |
| 5.4.99.7 | OSC | - |
Saccharomyces cerevisiae |
| 5.4.99.7 | Oxidosqualene-lanosterol cyclase | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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