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Literature summary extracted from

  • Chevalier, C.; Huntzinger, E.; Fechter, P.; Boisset, S.; Vandenesch, F.; Romby, P.; Geissmann, T.
    Staphylococcus aureus endoribonuclease III purification and properties (2008), Methods Enzymol., 447, 309-327.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.26.3 overexpressed in Escherichia coli Staphylococcus aureus

Protein Variants

EC Number Protein Variants Comment Organism
3.1.26.3 additional information rnc mutant (obtained by homologous recombination) is viable. Deletion of the rnc gene in Staphylococcus aureus does not affect cell growth in rich medium Staphylococcus aureus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.26.3 Ca2+ recombinant Sa-RNase III is inhibited by Ca2+ Staphylococcus aureus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.26.3 Mg2+ recombinant Sa-RNase III requires MgCl2 for activity Staphylococcus aureus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.26.3 27900
-
homodimer of 243 amino acid polypeptides Staphylococcus aureus

Organism

EC Number Organism UniProt Comment Textmining
3.1.26.3 Staphylococcus aureus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.26.3
-
Staphylococcus aureus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.26.3 dsRNA + H2O process double-stranded RNAs consisting of two turns of the RNA helix. Although the enzyme plays a role in ribosomal RNA processing and gene regulation, enzyme is not essential for cell growth but regulates virulence gene expression Staphylococcus aureus mature RNA
-
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Subunits

EC Number Subunits Comment Organism
3.1.26.3 homodimer
-
Staphylococcus aureus

Synonyms

EC Number Synonyms Comment Organism
3.1.26.3 endoribonuclease III
-
Staphylococcus aureus
3.1.26.3 Sa-RNase III
-
Staphylococcus aureus