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Literature summary extracted from

  • Ye, Z.Q.; Kong, D.B.; Chen, Z.Q.; Yao, L.F.; Guo, H.; Yu, X.; Liu, G.L.; Yang, W.M.
    Stable expression of the oxc and frc genes from Oxalobacter formigenes in human embryo kidney 293 cells: implications for gene therapy of hyperoxaluria (2007), Int. J. Mol. Med., 20, 521-526.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.8.3.16 medicine gene therapy of hyperoxaluria Oxalobacter formigenes

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.3.16 stable expression in human embryo kidney 293 cells Oxalobacter formigenes

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.3.16 cytoplasm of transfected HEK-293 cells Oxalobacter formigenes 5737
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.3.16 formyl-CoA + oxalate Oxalobacter formigenes oxalyl-CoA decarboxylase and formyl-CoA transferase are the key enzymes in the oxalate catabolism of Oxalobacter formigenes which dwell in the intestine of vertebrates and have an important symbiotic relationship with their hosts formate + oxalyl-CoA
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.3.16 Oxalobacter formigenes
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 present in the intestine of Homo sapiens, the strain was isolated from fecal samples of healthy Chinese
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.3.16 formyl-CoA + oxalate
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 Oxalobacter formigenes formate + oxalyl-CoA
-
 ?
2.8.3.16 formyl-CoA + oxalate oxalyl-CoA decarboxylase and formyl-CoA transferase are the key enzymes in the oxalate catabolism of Oxalobacter formigenes which dwell in the intestine of vertebrates and have an important symbiotic relationship with their hosts Oxalobacter formigenes formate + oxalyl-CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.3.16 formyl-CoA-transferase
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 Oxalobacter formigenes
2.8.3.16 FRC
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 Oxalobacter formigenes