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Literature summary extracted from

  • Yadav, S.K.; Singla-Pareek, S.L.; Sopory, S.K.
    An overview on the role of methylglyoxal and glyoxalases in plants (2008), Drug Metabol. Drug Interact., 23, 51-68.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.2.6 auxin enhances activity of both gly I and II Glycine max
3.1.2.6 additional information coldnesse enhances gly II transcript expression Brassica sp.
3.1.2.6 additional information drought enhances gly II transcript expression Brassica sp.
3.1.2.6 additional information salt enhances gly II transcript expression Brassica sp.
3.1.2.6 additional information zinc stress enhances gly II transcript expression Brassica sp.
4.4.1.5 6-benzylaminopurine
-
Pisum sativum
4.4.1.5 6-benzylaminopurine
-
Nicotiana sp.
4.4.1.5 abscisic acid
-
Solanum tuberosum
4.4.1.5 auxin enhances activity of both gly I and II in Glycine max Glycine max
4.4.1.5 indole acetic acid stimulation of activity of glyoxalase I Pisum sativum
4.4.1.5 kinetin
-
Pisum sativum
4.4.1.5 kinetin
-
Nicotiana sp.
4.4.1.5 light red and blue light exposure increases gly I activity in dark-gron Amaranthus sp. indicating expression of enzyme is under stringent regulation by photoreceptors in plants Amaranthus sp.
4.4.1.5 mannitol
-
Solanum tuberosum
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxai, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Amaranthus sp.
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Triticum aestivum
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Pisum sativum
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Solanum tuberosum
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Glycine max
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Oryza sativa
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Nicotiana sp.
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Brassica sp.
4.4.1.5 additional information not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I Aloe vera
4.4.1.5 spermidine
-
Triticum aestivum
4.4.1.5 spermidine
-
Pisum sativum
4.4.1.5 spermidine
-
Solanum tuberosum
4.4.1.5 spermidine gly I Amaranthus sp.
4.4.1.5 spermidine gly I Oryza sativa
4.4.1.5 spermidine gly I Nicotiana sp.
4.4.1.5 spermidine gly I Aloe vera

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.2.6
-
Arabidopsis thaliana
3.1.2.6 Brassica sp. gly II Brassica sp.
4.4.1.5 Brassica sp. gly I, cloning and overexpression in tobacco, transgenic plants tolerate higher concentrations of NaCl Glycine max
4.4.1.5 Brassica sp. gly I, cloning and overexpression in tobacco, transgenic plants tolerate higher concentrations of NaCl Brassica sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.2.6 N,S-bis-carbobenzoxy-glutathione
-
Arabidopsis thaliana
3.1.2.6 N,S-bis-FMOC-glutathione
-
Arabidopsis thaliana
4.4.1.5 1-Naphthaleneacetic acid activity decreases by approximately 50% during differentiation in Brassica sp. gly I Brassica sp.
4.4.1.5 1-Naphthaleneacetic acid activity decreases by approximately 50% during differentiation in Brassica sp. gly I Oryza sativa
4.4.1.5 benzyladenine activity decreases by approximately 50% during differentiation in Brassica sp. gly I Brassica sp.
4.4.1.5 benzyladenine activity decreases by approximately 50% during differentiation in Brassica sp. gly I Oryza sativa
4.4.1.5 Colchicine decrease of activity of glyoxalase I Oryza sativa
4.4.1.5 Colchicine decrease of activity of glyoxalase I Pisum sativum
4.4.1.5 vinblastine decrease of activity of glyoxalase I Oryza sativa
4.4.1.5 vinblastine decrease of activity of glyoxalase I Pisum sativum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.5 0.061
-
(R)-S-lactoylglutathione
-
Oryza sativa
4.4.1.5 0.12
-
(R)-S-lactoylglutathione Brassica sp. gly I Brassica sp.
4.4.1.5 1.4
-
methylglyoxal for the hemithioacetal as substrate Aloe vera

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.6 cytosol
-
Zea mays 5829
-
3.1.2.6 cytosol
-
Solanum tuberosum 5829
-
3.1.2.6 cytosol
-
Glycine max 5829
-
3.1.2.6 cytosol
-
Arabidopsis thaliana 5829
-
3.1.2.6 cytosol
-
Brassica sp. 5829
-
3.1.2.6 membrane associated Zea mays 16020
-
3.1.2.6 membrane associated Solanum tuberosum 16020
-
3.1.2.6 membrane associated Glycine max 16020
-
3.1.2.6 membrane associated Arabidopsis thaliana 16020
-
3.1.2.6 membrane associated Brassica sp. 16020
-
3.1.2.6 mitochondrion
-
Zea mays 5739
-
3.1.2.6 mitochondrion
-
Solanum tuberosum 5739
-
3.1.2.6 mitochondrion
-
Glycine max 5739
-
3.1.2.6 mitochondrion
-
Arabidopsis thaliana 5739
-
3.1.2.6 mitochondrion
-
Brassica sp. 5739
-
4.4.1.5 cytosol
-
Triticum aestivum 5829
-
4.4.1.5 cytosol
-
Pisum sativum 5829
-
4.4.1.5 cytosol
-
Amaranthus sp. 5829
-
4.4.1.5 cytosol
-
Solanum tuberosum 5829
-
4.4.1.5 cytosol
-
Glycine max 5829
-
4.4.1.5 cytosol
-
Oryza sativa 5829
-
4.4.1.5 cytosol
-
Nicotiana sp. 5829
-
4.4.1.5 cytosol
-
Brassica sp. 5829
-
4.4.1.5 cytosol
-
Aloe vera 5829
-
4.4.1.5 membrane associated Triticum aestivum 16020
-
4.4.1.5 membrane associated Pisum sativum 16020
-
4.4.1.5 membrane associated Amaranthus sp. 16020
-
4.4.1.5 membrane associated Solanum tuberosum 16020
-
4.4.1.5 membrane associated Glycine max 16020
-
4.4.1.5 membrane associated Oryza sativa 16020
-
4.4.1.5 membrane associated Nicotiana sp. 16020
-
4.4.1.5 membrane associated Brassica sp. 16020
-
4.4.1.5 membrane associated Aloe vera 16020
-
4.4.1.5 mitochondrion
-
Triticum aestivum 5739
-
4.4.1.5 mitochondrion
-
Pisum sativum 5739
-
4.4.1.5 mitochondrion
-
Amaranthus sp. 5739
-
4.4.1.5 mitochondrion
-
Solanum tuberosum 5739
-
4.4.1.5 mitochondrion
-
Glycine max 5739
-
4.4.1.5 mitochondrion
-
Oryza sativa 5739
-
4.4.1.5 mitochondrion
-
Nicotiana sp. 5739
-
4.4.1.5 mitochondrion
-
Brassica sp. 5739
-
4.4.1.5 mitochondrion
-
Aloe vera 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.2.6 Fe3+ Arabidopsis thaliana mitochondrial and cytosolic gly II can accomodate a number of different metal centers, enzyme contains an iron-zinc binuclear metal center that os essential for activity Arabidopsis thaliana
3.1.2.6 Mn2+ no binding to Arabidopsis thaliana mitochondrial enzyme, but binding to cytosolic gly II Arabidopsis thaliana
3.1.2.6 Zn2+ binding affinity Zea mays
3.1.2.6 Zn2+ binding affinity Solanum tuberosum
3.1.2.6 Zn2+ binding affinity Glycine max
3.1.2.6 Zn2+ binding affinity Arabidopsis thaliana
3.1.2.6 Zn2+ binding affinity Brassica sp.
4.4.1.5 Ca2+ activation of gly I Triticum aestivum
4.4.1.5 Ca2+ activation of gly I Pisum sativum
4.4.1.5 Ca2+ activation of gly I Amaranthus sp.
4.4.1.5 Ca2+ activation of gly I Solanum tuberosum
4.4.1.5 Ca2+ activation of gly I Glycine max
4.4.1.5 Ca2+ activation of gly I Oryza sativa
4.4.1.5 Ca2+ activation of gly I Nicotiana sp.
4.4.1.5 Ca2+ activation of gly I Brassica sp.
4.4.1.5 Ca2+ activation of gly I Aloe vera
4.4.1.5 Zn2+ activates Brassica juncea
4.4.1.5 Zn2+ binding affinity Triticum aestivum
4.4.1.5 Zn2+ binding affinity Pisum sativum
4.4.1.5 Zn2+ binding affinity Amaranthus sp.
4.4.1.5 Zn2+ binding affinity Solanum tuberosum
4.4.1.5 Zn2+ binding affinity Glycine max
4.4.1.5 Zn2+ binding affinity Oryza sativa
4.4.1.5 Zn2+ binding affinity Nicotiana sp.
4.4.1.5 Zn2+ binding affinity Brassica sp.
4.4.1.5 Zn2+ binding affinity Aloe vera

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.2.6 26000
-
Zea mays gly II enzyme is a monomer Zea mays
4.4.1.5 37000
-
-
Triticum aestivum
4.4.1.5 37000
-
Triticum aestivum gly I enzyme is a monomer Triticum aestivum
4.4.1.5 44000
-
-
Aloe vera
4.4.1.5 44000
-
enzyme is a monomer Aloe vera
4.4.1.5 58000
-
-
Brassica oleracea
4.4.1.5 58000
-
Brassica gly I enzyme Brassica sp.
4.4.1.5 60000
-
enzyme has two subunits Glycine max

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.6 additional information Zea mays the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
3.1.2.6 additional information Solanum tuberosum the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
3.1.2.6 additional information Glycine max the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
3.1.2.6 additional information Arabidopsis thaliana the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
3.1.2.6 additional information Brassica sp. the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
3.1.2.6 S-D-lactoylglutathione + H2O Zea mays second step in the glyoxalase system D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O Solanum tuberosum second step in the glyoxalase system D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O Glycine max second step in the glyoxalase system D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O Arabidopsis thaliana second step in the glyoxalase system D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O Brassica sp. second step in the glyoxalase system D-lactate + glutathione
-
?
4.4.1.5 methylglyoxal + glutathione Triticum aestivum first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Pisum sativum first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Solanum tuberosum first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Glycine max first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Oryza sativa first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Nicotiana sp. first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Brassica sp. first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Aloe vera first step in the glyoxalase system (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione Amaranthus sp. first step in the glyoxalase system (R)S-lactoylglutathione
-
r
4.4.1.5 additional information Triticum aestivum the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Pisum sativum the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Amaranthus sp. the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Solanum tuberosum the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Glycine max the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Oryza sativa the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Nicotiana sp. the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Brassica sp. the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?
4.4.1.5 additional information Aloe vera the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.6 Arabidopsis thaliana
-
-
-
3.1.2.6 Brassica sp.
-
-
-
3.1.2.6 Glycine max
-
soybean
-
3.1.2.6 Solanum tuberosum
-
-
-
3.1.2.6 Zea mays
-
-
-
4.4.1.5 Aloe vera
-
-
-
4.4.1.5 Amaranthus sp.
-
-
-
4.4.1.5 Brassica juncea
-
-
-
4.4.1.5 Brassica oleracea
-
-
-
4.4.1.5 Brassica sp.
-
-
-
4.4.1.5 Glycine max
-
soybean
-
4.4.1.5 Nicotiana sp.
-
-
-
4.4.1.5 Oryza sativa
-
-
-
4.4.1.5 Pisum sativum
-
-
-
4.4.1.5 Solanum lycopersicum
-
-
-
4.4.1.5 Solanum tuberosum
-
-
-
4.4.1.5 Triticum aestivum
-
-
-
4.4.1.5 Triticum aestivum
-
wheat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.2.6
-
Zea mays
3.1.2.6 Arabidopsis thaliana gly II Arabidopsis thaliana
3.1.2.6 Brassica sp. gly II Brassica sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.6 flower bud differential expression of mitochondrial and cytosolic gly II Arabidopsis thaliana
-
3.1.2.6 flower bud differential expression of mitochondrial and cytosolic gly II Brassica sp.
-
3.1.2.6 leaf gly II Zea mays
-
3.1.2.6 leaf gly II Arabidopsis thaliana
-
3.1.2.6 leaf gly II Brassica sp.
-
3.1.2.6 root differential expression of mitochondrial and cytosolic gly II Zea mays
-
3.1.2.6 root differential expression of mitochondrial and cytosolic gly II Arabidopsis thaliana
-
3.1.2.6 root differential expression of mitochondrial and cytosolic gly II Brassica sp.
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Triticum aestivum
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Pisum sativum
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Amaranthus sp.
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Solanum tuberosum
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Glycine max
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Oryza sativa
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Nicotiana sp.
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Brassica sp.
-
4.4.1.5 additional information gly I is present in all types of cells and tissues Aloe vera
-
4.4.1.5 additional information present in all types of cells and tissues Solanum lycopersicum
-
4.4.1.5 phloem
-
Triticum aestivum
-
4.4.1.5 phloem
-
Pisum sativum
-
4.4.1.5 phloem
-
Amaranthus sp.
-
4.4.1.5 phloem
-
Solanum tuberosum
-
4.4.1.5 phloem
-
Glycine max
-
4.4.1.5 phloem
-
Oryza sativa
-
4.4.1.5 phloem
-
Nicotiana sp.
-
4.4.1.5 phloem
-
Brassica sp.
-
4.4.1.5 phloem
-
Aloe vera
-
4.4.1.5 phloem preferentially accumulated in phloem and sieve cells Solanum lycopersicum
-
4.4.1.5 sieve cell
-
Triticum aestivum
-
4.4.1.5 sieve cell
-
Pisum sativum
-
4.4.1.5 sieve cell
-
Amaranthus sp.
-
4.4.1.5 sieve cell
-
Solanum tuberosum
-
4.4.1.5 sieve cell
-
Glycine max
-
4.4.1.5 sieve cell
-
Oryza sativa
-
4.4.1.5 sieve cell
-
Nicotiana sp.
-
4.4.1.5 sieve cell
-
Brassica sp.
-
4.4.1.5 sieve cell
-
Aloe vera
-
4.4.1.5 sieve cell preferentially accumulated in phloem and sieve cells Solanum lycopersicum
-
4.4.1.5 tuber found to be conserved in tubers among different potato variants Solanum tuberosum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.4.1.5 additional information
-
activity of glyoxalase I in Pisum sativum shows linear progression with development of shoots and roots of seedlings, cell division and proliferation further modulate the activity Pisum sativum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.6 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Zea mays ?
-
?
3.1.2.6 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Solanum tuberosum ?
-
?
3.1.2.6 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Glycine max ?
-
?
3.1.2.6 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Arabidopsis thaliana ?
-
?
3.1.2.6 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Brassica sp. ?
-
?
3.1.2.6 S-D-lactoylglutathione + H2O second step in the glyoxalase system Zea mays D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O second step in the glyoxalase system Solanum tuberosum D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O second step in the glyoxalase system Glycine max D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O second step in the glyoxalase system Arabidopsis thaliana D-lactate + glutathione
-
?
3.1.2.6 S-D-lactoylglutathione + H2O second step in the glyoxalase system Brassica sp. D-lactate + glutathione
-
?
4.4.1.5 glutathione + methylglyoxal
-
Aloe vera S-D-lactoylglutathione
-
?
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Triticum aestivum (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Pisum sativum (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Solanum tuberosum (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Glycine max (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Oryza sativa (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Nicotiana sp. (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Brassica sp. (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Aloe vera (R)-S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione first step in the glyoxalase system Amaranthus sp. (R)S-lactoylglutathione
-
r
4.4.1.5 methylglyoxal + glutathione non-enzymatic formation of hemithioacteal as substrate for gly I Aloe vera S-((R)-lactoyl)glutathione
-
?
4.4.1.5 methylglyoxal + glutathione non-enzymatic formation of hemithioacteal as substrate for gly I. The active site of gly I has binding affinity for zinc ion and hemithioacetal, and his His residue might be important for its catalytic activity Brassica juncea S-((R)-lactoyl)glutathione
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Triticum aestivum ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Pisum sativum ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Amaranthus sp. ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Solanum tuberosum ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Glycine max ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Oryza sativa ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Nicotiana sp. ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Brassica sp. ?
-
?
4.4.1.5 additional information the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes Aloe vera ?
-
?

Subunits

EC Number Subunits Comment Organism
3.1.2.6 monomer
-
Zea mays
4.4.1.5 dimer 2 * 27000-29000 Brassica oleracea
4.4.1.5 heterodimer enzyme has 2 subunits Brassica sp.
4.4.1.5 heterodimer Glycine max gly I enzyme has 2 subunits Glycine max
4.4.1.5 monomer 1 * 37000 Triticum aestivum
4.4.1.5 monomer 1 * 44000 Aloe vera
4.4.1.5 monomer Aloe vera gly I Aloe vera

Synonyms

EC Number Synonyms Comment Organism
3.1.2.6 glyoxalase II
-
Zea mays
3.1.2.6 glyoxalase II
-
Solanum tuberosum
3.1.2.6 glyoxalase II
-
Glycine max
3.1.2.6 glyoxalase II
-
Arabidopsis thaliana
3.1.2.6 glyoxalase II
-
Brassica sp.
3.1.2.6 hydroxyacylglutathione hydrolase
-
Zea mays
3.1.2.6 hydroxyacylglutathione hydrolase
-
Solanum tuberosum
3.1.2.6 hydroxyacylglutathione hydrolase
-
Glycine max
3.1.2.6 hydroxyacylglutathione hydrolase
-
Arabidopsis thaliana
3.1.2.6 hydroxyacylglutathione hydrolase
-
Brassica sp.
4.4.1.5 glyoxalase I
-
Triticum aestivum
4.4.1.5 glyoxalase I
-
Pisum sativum
4.4.1.5 glyoxalase I
-
Amaranthus sp.
4.4.1.5 glyoxalase I
-
Solanum tuberosum
4.4.1.5 glyoxalase I
-
Glycine max
4.4.1.5 glyoxalase I
-
Oryza sativa
4.4.1.5 glyoxalase I
-
Nicotiana sp.
4.4.1.5 glyoxalase I
-
Brassica sp.
4.4.1.5 glyoxalase I
-
Aloe vera
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Triticum aestivum
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Pisum sativum
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Amaranthus sp.
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Solanum tuberosum
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Glycine max
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Oryza sativa
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Nicotiana sp.
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Brassica sp.
4.4.1.5 lactoylglutathione methylglyoxal lyase
-
Aloe vera

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.5 glutathione
-
Triticum aestivum
4.4.1.5 glutathione
-
Pisum sativum
4.4.1.5 glutathione
-
Amaranthus sp.
4.4.1.5 glutathione
-
Solanum tuberosum
4.4.1.5 glutathione
-
Glycine max
4.4.1.5 glutathione
-
Oryza sativa
4.4.1.5 glutathione
-
Nicotiana sp.
4.4.1.5 glutathione
-
Brassica sp.
4.4.1.5 glutathione
-
Aloe vera

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.2.6 0.89
-
N,S-bis-FMOC-glutathione
-
Arabidopsis thaliana
3.1.2.6 2.3
-
di-carbobenzoxyglutathione
-
Arabidopsis thaliana

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.1.2.6 Zea mays acidic pI of plant gly II ranges from 4.5-6.2
-
additional information
3.1.2.6 Solanum tuberosum acidic pI of plant gly II ranges from 4.5-6.2
-
additional information
3.1.2.6 Glycine max acidic pI of plant gly II ranges from 4.5-6.2
-
additional information
3.1.2.6 Arabidopsis thaliana acidic pI of plant gly II ranges from 4.5-6.2
-
additional information
3.1.2.6 Brassica sp. acidic pI of plant gly II ranges from 4.5-6.2
-
additional information
4.4.1.5 Triticum aestivum plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Pisum sativum plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Amaranthus sp. plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Solanum tuberosum plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Glycine max plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Nicotiana sp. plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Brassica sp. plant gly I ranges from 4.7-5.1
-
additional information
4.4.1.5 Aloe vera
-
-
7.8
4.4.1.5 Oryza sativa mitochondrial form of Oryza sativa gly I
-
8.1