EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.4.3 | overexpression in Escherichia coli | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.4.3 | ADP + TDP | Escherichia coli | Escherichia coli adenylate kinase is able to synthesize TTP, but the activity is too low to explain the high rate of TTP accumulation uring amino acid starvation of cells | AMP + TTP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.4.3 | Escherichia coli | - |
- |
- |
2.7.4.15 | Escherichia coli | - |
BL21 strain and heat-sensitive CV2, CGSC 4682 strain | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.4.15 | additional information | - |
thiamine triphoshate accumulation in response to amino acid starvation, controverse mechanism of synthesis dicussed, adenylate kinase-independent accumulation of thiamine triphosphate, heat-sensitive CV2 strain of Escherichia coli accumulates thiamine triphosphate despite full inactivation of adenylate cyclase and subsequent decrease of cellular ATP, ATP-dependent mechanisms for thiamine triphosphate synthesis not favoured since large accumulation also observed during energy stress where ATP is low | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.4.3 | ADP | - |
Escherichia coli | AMP + ATP | - |
? | |
2.7.4.3 | ADP + TDP | Escherichia coli adenylate kinase is able to synthesize TTP, but the activity is too low to explain the high rate of TTP accumulation uring amino acid starvation of cells | Escherichia coli | AMP + TTP | - |
? | |
2.7.4.3 | ADP + TDP | rate of TTP synthesis is more than 1000000fold lower than ATP synthesis | Escherichia coli | AMP + TTP | - |
? | |
2.7.4.15 | additional information | enzymatic synthesis of thiamine triphosphate in Escherichia coli | Escherichia coli | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.4.15 | thiamine diphosphate kinase | - |
Escherichia coli |