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Literature summary extracted from
- Small-scale immunopurification of cytochrome c oxidase for a high-throughput multiplexing analysis of enzyme activity and amount (2007), Biotechnol. Appl. Biochem., 48, 167-178.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 7.1.1.9 | medicine | COX deficiency is a common cause of human mitochondrial disease | Homo sapiens |
| 7.1.1.9 | additional information | simple and rapid isolation of COX by immunocapture | Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.9 | CN- | - |
Homo sapiens |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.1.1.9 | membrane | - |
Bos taurus | 16020 | - |
| 7.1.1.9 | mitochondrion | - |
Homo sapiens | 5739 | - |
| 7.1.1.9 | mitochondrion | - |
Bos taurus | 5739 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.9 | Bos taurus | - |
- |
- |
| 7.1.1.9 | Bos taurus | P00396 | - |
- |
| 7.1.1.9 | Bos taurus | P00415 | - |
- |
| 7.1.1.9 | Bos taurus | P00423 | - |
- |
| 7.1.1.9 | Bos taurus | P00426 | - |
- |
| 7.1.1.9 | Bos taurus | P00428 | - |
- |
| 7.1.1.9 | Bos taurus | P00429 | - |
- |
| 7.1.1.9 | Bos taurus | P00430 | - |
- |
| 7.1.1.9 | Bos taurus | P04038 | - |
- |
| 7.1.1.9 | Bos taurus | P07470 | - |
- |
| 7.1.1.9 | Bos taurus | P07471 | - |
- |
| 7.1.1.9 | Bos taurus | P10175 | - |
- |
| 7.1.1.9 | Bos taurus | P13183 | - |
- |
| 7.1.1.9 | Bos taurus | P13184 | - |
- |
| 7.1.1.9 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.1.1.9 | by small-scale immunopurification | Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 7.1.1.9 | fibroblast | - |
Homo sapiens | - |
| 7.1.1.9 | fibroblast | - |
Bos taurus | - |
| 7.1.1.9 | heart | - |
Homo sapiens | - |
| 7.1.1.9 | heart | - |
Bos taurus | - |
| 7.1.1.9 | kidney | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Homo sapiens | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Bos taurus | ferricytochrome c + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.1.1.9 | COX | - |
Homo sapiens |
| 7.1.1.9 | COX I | - |
Bos taurus |
| 7.1.1.9 | COX II | - |
Bos taurus |
| 7.1.1.9 | COX III | - |
Bos taurus |
| 7.1.1.9 | COX IV | - |
Bos taurus |
| 7.1.1.9 | COX Va | - |
Bos taurus |
| 7.1.1.9 | COX Vb | - |
Bos taurus |
| 7.1.1.9 | COX VIa-H | - |
Bos taurus |
| 7.1.1.9 | COX VIb | - |
Bos taurus |
| 7.1.1.9 | COX VIc | - |
Bos taurus |
| 7.1.1.9 | COX VIIa H | - |
Bos taurus |
| 7.1.1.9 | COX VIIa L | - |
Bos taurus |
| 7.1.1.9 | COX VIIb | - |
Bos taurus |
| 7.1.1.9 | COX VIIc | - |
Bos taurus |
| 7.1.1.9 | COX VIII | - |
Bos taurus |
| 7.1.1.9 | cytochrome c oxidase | - |
Homo sapiens |
| 7.1.1.9 | cytochrome c oxidase | - |
Bos taurus |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 7.1.1.9 | 0.001 | - |
- |
Homo sapiens | CN- | |
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Release 2023.1 (January 2023)
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