BRENDA - Enzyme Database

Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae

Teske, B.; Taramino, S.; Bhuiyan, M.S.; Kumaraswami, N.S.; Randall, S.K.; Barbuch, R.; Eckstein, J.; Balliano, G.; Bard, M.; Biochim. Biophys. Acta 1781, 359-366 (2008)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
5.4.99.7
Erg27p
required for activity of Erg7p
Saccharomyces cerevisiae
Organism
EC Number
Organism
UniProt
Commentary
Textmining
5.4.99.7
Saccharomyces cerevisiae
-
-
-
5.4.99.7
Saccharomyces cerevisiae SCY876
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
5.4.99.7
(S)-2,3-oxidosqualene
-
691073
Saccharomyces cerevisiae
lanosterol
-
-
-
?
5.4.99.7
(S)-2,3-oxidosqualene
-
691073
Saccharomyces cerevisiae SCY876
lanosterol
-
-
-
?
Synonyms
EC Number
Synonyms
Commentary
Organism
5.4.99.7
Erg7p
-
Saccharomyces cerevisiae
5.4.99.7
oxidosqualene cyclase/lanosterol synthase
-
Saccharomyces cerevisiae
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
5.4.99.7
Erg27p
required for activity of Erg7p
Saccharomyces cerevisiae
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
5.4.99.7
(S)-2,3-oxidosqualene
-
691073
Saccharomyces cerevisiae
lanosterol
-
-
-
?
5.4.99.7
(S)-2,3-oxidosqualene
-
691073
Saccharomyces cerevisiae SCY876
lanosterol
-
-
-
?