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Literature summary extracted from

  • Song, Y.; Choi, M.H.; Park, J.N.; Kim, M.W.; Kim, E.J.; Kang, H.A.; Kim, J.Y.
    Engineering of the yeast Yarrowia lipolytica for the production of glycoproteins lacking the outer-chain mannose residues of N-glycans (2007), Appl. Environ. Microbiol., 73, 4446-4454.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.4.1.232 drug development along with the possibility of a lack of the immunogenic terminal alpha-1,3-mannose linkages in Yarrowia lipolytica, a Yloch1delta mutant strain can be exploited as a platform strain for developing another potential yeast system that can produce recombinant glycoproteins with human-compatible oligosaccharides Yarrowia lipolytica

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.232 into the pGEMT-Easy vector Yarrowia lipolytica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.232 membrane
-
 Yarrowia lipolytica 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.232 additional information Yarrowia lipolytica transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1-6)-D-mannosyl-D-mannose linkage ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.232 Yarrowia lipolytica
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.232 additional information transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1-6)-D-mannosyl-D-mannose linkage Yarrowia lipolytica ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.232 alpha-1,6-mannosyltransferase
-
 Yarrowia lipolytica
2.4.1.232 initiation-specific alpha-1,6-mannosyltransferase
-
 Yarrowia lipolytica
2.4.1.232 YlOch1p
-
 Yarrowia lipolytica

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.232 30
-
 in vitro alpha-1,6-mannosyltransferase activity assay Yarrowia lipolytica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.232 7.5
-
 in vitro alpha-1,6-mannosyltransferase activity assay Yarrowia lipolytica