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Literature summary extracted from

  • Olson, K.R.; Healy, M.J.; Qin, Z.; Skovgaard, N.; Vulesevic, B.; Duff, D.W.; Whitfield, N.L.; Yang, G.; Wang, R.; Perry, S.F.
    Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors (2008), Am. J. Physiol. Regul. Integr. Comp. Physiol., 295, R669-R680.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 O2 homogenized gills produces H2S enzymatically, and H2S production is inhibited by O2, whereas mitchondrial H2S consumption is O2 dependent Oncorhynchus mykiss
4.4.1.1 propargyl glycine
-
 Oncorhynchus mykiss

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.4.1.1 mitochondrion
-
 Oncorhynchus mykiss 5739
-

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Danio rerio
-
-
-
4.4.1.1 Oncorhynchus mykiss
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.1 artery
-
 Oncorhynchus mykiss
-
4.4.1.1 brain
-
 Oncorhynchus mykiss
-
4.4.1.1 branchial tissue
-
 Oncorhynchus mykiss
-
4.4.1.1 gill
-
 Oncorhynchus mykiss
-
4.4.1.1 heart
-
 Oncorhynchus mykiss
-
4.4.1.1 liver
-
 Oncorhynchus mykiss
-
4.4.1.1 neuroepithelial cell
-
 Danio rerio
-
4.4.1.1 skeletal muscle
-
 Oncorhynchus mykiss
-
4.4.1.1 vascular smooth muscle
-
 Oncorhynchus mykiss
-
4.4.1.1 vein
-
 Oncorhynchus mykiss
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cysteine + H2O
-
 Oncorhynchus mykiss sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Danio rerio sulfide + NH3 + pyruvate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 CSE
-
 Oncorhynchus mykiss
4.4.1.1 CSE
-
 Danio rerio
4.4.1.1 cystathionine gamma-lyase
-
 Oncorhynchus mykiss
4.4.1.1 cystathionine gamma-lyase
-
 Danio rerio

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.1 pyridoxal 5'-phosphate
-
 Oncorhynchus mykiss
4.4.1.1 pyridoxal 5'-phosphate
-
 Danio rerio