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Literature summary extracted from

  • Gregus, Z.; Nemeti, B.
    Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors (2007), Toxicol. Sci., 100, 44-53.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.1 AMP activates Oryctolagus cuniculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 1,4-dideoxy-1,4-imino-D-arabinitol inhibits Pa-catalyzed As(V) reduction, inhibition of As(V) reduction is not influenced by glucose or AMP Oryctolagus cuniculus
2.4.1.1 ADP at physiological levels diminishes GPa-catalyzed As(V) reduction Oryctolagus cuniculus
2.4.1.1 ATP at physiological levels diminishes GPa-catalyzed As(V) reduction Oryctolagus cuniculus
2.4.1.1 BAY U6751 inhibits Pa-catalyzed As(V) reduction, glucose enhances inhibitory effect of the inhibitor on As(V) reduction, AMP at high concentration alleviates the inhibition Oryctolagus cuniculus
2.4.1.1 CP320626 inhibits Pa-catalyzed As(V) reduction, glucose enhances inhibitory effect of the inhibitor on As(V) reduction, AMP at high concentration alleviated the inhibition Oryctolagus cuniculus
2.4.1.1 glucose above 5 mM, diminishes GPa-catalyzed As(V) reduction Oryctolagus cuniculus
2.4.1.1 NEM inhibits GPa-catalyzed As(V) reduction Oryctolagus cuniculus
2.4.1.1 p-chloromercuribenzene sulfonate inhibits GPa-catalyzed As(V) reduction Oryctolagus cuniculus
2.4.1.1 quercetin inhibits Pa-catalyzed As(V) reduction, inhibition of As(V) reduction is not influenced by glucose or AMP Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.1 muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.1 additional information GPa reduces arsenate (As(V)) to the more toxic arsenite (As(III)) in a glutathione (GSH)-dependent fashion Oryctolagus cuniculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.1 glycogen phosphorylase-a
-
 Oryctolagus cuniculus
2.4.1.1 GPA
-
 Oryctolagus cuniculus