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Literature summary extracted from

  • Carpene, C.; Iffiu-Soltesz, Z.; Bour, S.; Prevot, D.; Valet, P.
    Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats (2007), Pharmacol. Res., 56, 522-530.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 Pargyline irreversible inhibitor. Pargyline + semicarbazide-induced reduction of fat deposition results from decreased food intake and from impaired MAO and SSAO-dependent lipogenic and antilipolytic actions of endogenous or alimentary amines Rattus norvegicus
1.4.3.21 Semicarbazide irreversible inhibitor. Pargyline + semicarbazide-induced reduction of fat deposition results from decreased food intake and from impaired MAO (EC 1.4.3.4) and SSAO-dependent lipogenic and antilipolytic actions of endogenous or alimentary amines Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Rattus norvegicus
-
-
-
1.4.3.21 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 benzylamine + H2O + O2
-
Rattus norvegicus benzaldehyde + NH3 + H2O2
-
?
1.4.3.4 tyramine + H2O + O2
-
Rattus norvegicus 4-hydroxyphenylethanal + NH3 + H2O2
-
?
1.4.3.21 benzylamine + H2O + O2
-
Rattus norvegicus benzaldehyde + NH3 + H2O2
-
?
1.4.3.21 tyramine + H2O + O2
-
Rattus norvegicus 4-hydroxyphenylethanal + NH3 + H2O2
-
?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO
-
Rattus norvegicus
1.4.3.21 SSAO
-
Rattus norvegicus