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Literature summary extracted from

  • Eissenberg, J.C.; Lee, M.G.; Schneider, J.; Ilvarsonn, A.; Shiekhattar, R.; Shilatifard, A.
    The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase (2007), Nat. Struct. Mol. Biol., 14, 344-346.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.67 [histone-H3]-trimethyllysine4 + 2-oxoglutarate + O2 Drosophila melanogaster Lid knockdown using RNA interference results in a specific genome-wide increase in H3K4me3 levels without affecting other patterns of H3 methylation ?
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Organism

EC Number Organism UniProt Comment Textmining
1.14.11.67 Drosophila melanogaster Q9VMJ7
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Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.67 [histone-H3]-trimethyllysine4 + 2-oxoglutarate + O2 Lid knockdown using RNA interference results in a specific genome-wide increase in H3K4me3 levels without affecting other patterns of H3 methylation Drosophila melanogaster ?
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?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.67 H3K4me3 demethylase
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Drosophila melanogaster
1.14.11.67 Lid
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Drosophila melanogaster
1.14.11.67 little imaginal discs
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Drosophila melanogaster