Literature summary extracted from

Sabino, A.; Fernandes, A.P.; Lima, L.M.; Ribeiro, D.D.; Sousa, M.O.; de Castro Santos, M.E.; Mota, A.P.; Dusse, L.M.; das Gracas Carvalho, M.
Polymorphism in the methylenetetrahydrofolate reductase (C677T) gene and homocysteine levels: a comparison in Brazilian patients with coronary arterial disease, ischemic stroke and peripheral arterial obstructive disease (2009), J. Thromb. Thrombolysis, 27, 82-87.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.5.1.20	additional information	no significant correlation is demonstrated for C677T MTHFR gene polymorphism and homocysteine levels in Brazilian patients with coronary arterial disease, ischemic stroke, and peripheral arterial obstructive disease	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.20	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.5.1.20	blood	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.5.1.20	5,10-methylenetetrahydrofolate + reduced acceptor	-	Homo sapiens	5-methyltetrahydrofolate + oxidized acceptor	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.5.1.20	methylenetetrahydrofolate reductase	-	Homo sapiens
1.5.1.20	MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)