Literature summary extracted from

Harada, K.; Lin, H.; Endo, Y.; Fujishiro, N.; Sakamoto, Y.; Inoue, M.
Subunit composition and role of Na+,K+-ATPases in ventricular myocytes (2006), J. Physiol. Sci., 56, 113-121.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
7.2.2.13	sarcolemma	patchy presence of subunit isoform alpha1 in the transverse tubules and surface sarcolemma, isoform alpha2 is distributed continously in the tramsverse tubules alone. Isoform alpha3 is expressed prominently in the intercalated discs. Subunit isoform beta1 is located in the transverse tubules and surface sarcolemma, and isoform beta2 is mainly located in the intercalated disc	Cavia porcellus	42383	-
7.2.2.13	sarcolemma	patchy presence of subunit isoform alpha1 in the transverse tubules and surface sarcolemma, isoform alpha2 is distributed continuously in the transverse tubules alone. Isoform alpha3 is expressed slightly. Subunit isoform beta1 is located in the transverse tubules and surface sarcolemma, and isoform beta2 is mainly located in the intercalated disc	Rattus norvegicus	42383	-
7.2.2.13	transverse tubule	patchy presence of subunit isoform alpha1 in the transverse tubules and surface sarcolemma, isoform alpha2 is distributed continously in the tramsverse tubules alone. Isoform alpha3 is expressed prominently in the intercalated discs. Subunit isoform beta1 is located in the transverse tubules and surface sarcolemma, and isoform beta2 is mainly located in the intercalated disc	Cavia porcellus	-	-
7.2.2.13	transverse tubule	patchy presence of subunit isoform alpha1 in the transverse tubules and surface sarcolemma, isoform alpha2 is distributed continuously in the transverse tubules alone. Isoform alpha3 is expressed slightly. Subunit isoform beta1 is located in the transverse tubules and surface sarcolemma, and isoform beta2 is mainly located in the intercalated disc	Rattus norvegicus	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
7.2.2.13	Cavia porcellus	-	-	-
7.2.2.13	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
7.2.2.13	myocyte	ventricular myocyte. Patchy presence of subunit isoform alpha1 in the transverse tubules and surface sarcolemma, isoform alpha2 is distributed continously in the tramsverse tubules alone. Isoform alpha3 is expressed prominently in the intercalated discs. Subunit isoform beta1 is located in the transverse tubules and surface sarcolemma, and isoform beta2 is mainly located in the intercalated disc. Subunit isoform alpha1 and alpha2 form heterodimers with subunit isoform beta1 and alpha3 with beta2	Cavia porcellus	-
7.2.2.13	myocyte	ventricular myocyte. Patchy presence of subunit isoform alpha1 in the transverse tubules and surface sarcolemma, isoform alpha2 is distributed continuously in the transverse tubules alone. Isoform alpha3 is expressed slightly. Subunit isoform beta1 is located in the transverse tubules and surface sarcolemma, and isoform beta2 is mainly located in the intercalated disc. Subunit isoform alpha1 and alpha2 form heterodimers with subunit isoform beta1 and alpha3 with beta2	Rattus norvegicus	-

Subunits

EC Number	Subunits	Comment	Organism
7.2.2.13	More	subunit isoforms alpha1 and alpha2 form heterodimers with subunit isoform beta1 and alpha3 with beta2 in the ventricluar myocyte	Cavia porcellus
7.2.2.13	More	subunit isoforms alpha1 and alpha2 form heterodimers with subunit isoform beta1 and alpha3 with beta2 in the ventricluar myocyte	Rattus norvegicus

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Release 2023.1 (January 2023)