Literature summary extracted from

Smulders, Y.M.; Smith, D.E.; Kok, R.M.; Teerlink, T.; Gellekink, H.; Vaes, W.H.; Stehouwer, C.D.; Jakobs, C.
Red blood cell folate vitamer distribution in healthy subjects is determined by the methylenetetrahydrofolate reductase C677T polymorphism and by the total folate status (2007), J. Nutr. Biochem., 18, 693-699.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.5.1.20	additional information	the MTHFR C677T genotype is the dominant determinant of nonmethylfolate accumulation in red blood cells	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.20	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.5.1.20	erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.5.1.20	5,10-methylenetetrahydrofolate + reduced acceptor	-	Homo sapiens	5-methyltetrahydrofolate + oxidized acceptor	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.5.1.20	methylenetetrahydrofolate reductase	-	Homo sapiens
1.5.1.20	MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)