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Literature summary extracted from

  • Hanley, J.G.
    NSF binds calcium to regulate its interaction with AMPA receptor subunit GluR2 (2007), J. Neurochem., 101, 1644-1650.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.6.4.6 His6-NSF for expression in Escherichia coli BL21 cells Mammalia

Protein Variants

EC Number Protein Variants Comment Organism
3.6.4.6 D100A mutant to study the Ca2+ sensitivity of the interaction between NSF and the glutamate receptor subunit 2 of AMPAR Mammalia
3.6.4.6 D142A mutant to study the Ca2+ sensitivity of the interaction between NSF and the glutamate receptor subunit 2 of AMPAR Mammalia
3.6.4.6 E153A mutant to study the Ca2+ sensitivity of the interaction between NSF and the glutamate receptor subunit 2 of AMPAR Mammalia

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.4.6 synapse
-
 Mammalia 45202
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.4.6 Ca2+ NSF is a Ca2+-binding protein, GluR2-NSF interactions are inhibited by the presence of 15 micromol/l Ca2+ Mammalia

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.4.6 ATP + H2O Mammalia
-
 ADP + phosphate
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
3.6.4.6 Mammalia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.4.6 ATP + H2O
-
 Mammalia ADP + phosphate
-
 ir

Synonyms

EC Number Synonyms Comment Organism
3.6.4.6 N-ethylmaleimide-sensitive fusion protein
-
 Mammalia
3.6.4.6 NSF
-
 Mammalia