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Literature summary extracted from

  • McGregor, W.C.; Swierczek, S.I.; Bennett, B.; Holz, R.C.
    Characterization of the catalytically active Mn(II)-loaded argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli (2007), J. Biol. Inorg. Chem., 12, 603-613.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.16 [(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]leucine bestatin, competitive inhibitor Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.16 0.8
-
 N-alpha-acetyl-L-ornithine in 50 mM Chelex-100 treated sodium phosphate buffer, pH 7.5, at 25°C, in the presence of Mn2+ or Zn2+ Escherichia coli
3.5.1.16 1.2
-
 N-alpha-acetyl-L-ornithine in 50 mM Chelex-100 treated sodium phosphate buffer, pH 7.5, at 25°C, in the presence of Co2+ Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.1.16 Zn2+ dependent Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.1.16 42350
-
 calculated from amino acid sequence Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.16 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.16
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.16 N-alpha-acetyl-L-ornithine + H2O
-
 Escherichia coli ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.16 ArgE
-
 Escherichia coli
3.5.1.16 argE-encoded N-acetyl-L-ornithine deacetylase
-
 Escherichia coli

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.5.1.16 15 55
-
 Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.5.1.16 550
-
 N-alpha-acetyl-L-ornithine in 50 mM Chelex-100 treated sodium phosphate buffer, pH 7.5, at 25°C, in the presence of Mn2+ Escherichia coli
3.5.1.16 1600
-
 N-alpha-acetyl-L-ornithine in 50 mM Chelex-100 treated sodium phosphate buffer, pH 7.5, at 25°C, in the presence of Zn2+ Escherichia coli
3.5.1.16 3800
-
 N-alpha-acetyl-L-ornithine in 50 mM Chelex-100 treated sodium phosphate buffer, pH 7.5, at 25°C, in the presence of Co2+ Escherichia coli

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.5.1.16 0.067
-
 [(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]leucine
-
 Escherichia coli