EC Number | Cloned (Comment) | Organism |
---|---|---|
1.1.1.271 | DNA and amino acid sequence determination and analysis, enzyme expression in Mycobacterium bovis leads to restoration of wild-type phenotype producing triglycosylated phenolic glycolipids instead of monoglycosylated as in the mutant, mass spectrometric lipid spectrum analysis, overview | Mycobacterium tuberculosis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.271 | GDP-4-dehydro-6-deoxy-D-mannose + NADPH | Mycobacterium tuberculosis | the enzyme is required for the formation of activated L-fucose | GDP-L-fucose + NADP+ | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.271 | Mycobacterium tuberculosis | - |
- |
- |
1.1.1.271 | no activity in Mycobacterium bovis | - |
due to a natural mutation deleting the gene encoding the enzyme | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.271 | GDP-4-dehydro-6-deoxy-D-mannose + NADPH | - |
Mycobacterium tuberculosis | GDP-L-fucose + NADP+ | - |
r | |
1.1.1.271 | GDP-4-dehydro-6-deoxy-D-mannose + NADPH | the enzyme is required for the formation of activated L-fucose | Mycobacterium tuberculosis | GDP-L-fucose + NADP+ | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.271 | GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase/reductase | - |
Mycobacterium tuberculosis |