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Literature summary extracted from

  • Ozger, H.; Kilicoglu, O.; Yilmaz, H.; Ergen, H.A.; Yaylim, I.; Zeybek, U.; Isbir, T.
    Methylenetetrahydrofolate reductase C677T gene polymorphism in osteosarcoma and chondrosarcoma patients (2008), Folia Biol. (Praha), 54, 53-57.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.5.1.20 A222V no correlation can be proved between mutation, patient tumor site, presence of metastasis, and local tumor relapse, the polymorphism is not important in an individual's susceptibility to osteosarcoma and chondrosarcoma in Turkey and may not be a useful marker for identifying patients at high risk of developing sarcomas Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.20 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.20 leukocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.20 5,10-methylenetetrahydrofolate + reduced acceptor
-
Homo sapiens 5-methyltetrahydrofolate + oxidized acceptor
-
?

Synonyms

EC Number Synonyms Comment Organism
1.5.1.20 methylenetetrahydrofolate reductase
-
Homo sapiens
1.5.1.20 MTHFR
-
Homo sapiens