Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bartsch, R.; Steger, G.G.; Forstner, B.; Wenzel, C.; Pluschnig, U.; Rizovski, B.; Altorjai, G.; Zielinski, C.C.; Mader, R.M.
    Expression of thymidine phosphorylase in peripheral blood cells of breast cancer patients is not increased by paclitaxel (2007), BMC Clin. Pharmacol., 7, 7-7.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.4 additional information no activation of protein expression by paclitaxel, therefore no increased haematotoxicity due to thymidine phosphorylase upregulation is expected from the combination of taxanes and capecitabine Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.4 blood
-
 Homo sapiens
-
2.4.2.4 peripheral blood mononuclear cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.4 thymidine + phosphate
-
 Homo sapiens thymine + 2-deoxy-D-ribose 1-phosphate
-
 ?