Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Schue, M.; Glendinning, K.J.; Hobman, J.L.; Brown, N.L.
    Evidence for direct interactions between the mercuric ion transporter (MerT) and mercuric reductase (MerA) from the Tn501 mer operon (2008), Biometals, 21, 107-116.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.16.1.1 subcloning and expression in strain TG2, bacterial two hybrid assays are performed in strain BTH101 Escherichia coli K-12

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.16.1.1 cytoplasm
-
 Escherichia coli K-12 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.16.1.1 Hg2+ + NADPH Escherichia coli K-12 mercuric ion resistance in bacteria requires transport of Hg2+ ions into the cytoplasmic compartment where they are reduced to the less toxic metallic mercury Hg0 by mercuric reductase Hg(0) + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.16.1.1 Escherichia coli K-12
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.16.1.1 Hg2+ + NADPH mercuric ion resistance in bacteria requires transport of Hg2+ ions into the cytoplasmic compartment where they are reduced to the less toxic metallic mercury Hg0 by mercuric reductase Escherichia coli K-12 Hg(0) + NADP+
-
 r
1.16.1.1 Hg2+ + NADPH interactions between the inner membrane mercuric ion transporter, MerT, and the N-terminal domain of cytoplasmic mercuric reductase, transport is the rate-limiting step in mercury detoxification, overview Escherichia coli K-12 Hg(0) + NADP+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.16.1.1 mercuric ion reductase
-
 Escherichia coli K-12
1.16.1.1 mercuric reductase
-
 Escherichia coli K-12

Cofactor

EC Number Cofactor Comment Organism Structure
1.16.1.1 NADP+
-
 Escherichia coli K-12
1.16.1.1 NADPH
-
 Escherichia coli K-12